On-line water removal during enzymatic asymmetric esterification in organic media

L. Gubicza, A. Szakács-Schmidt

Research output: Contribution to journalArticle

7 Citations (Scopus)


Enantioselective esterification of 2-bromopropionic acid with n-butanol using Candida cylindracea lipase was carried out in n-pentane at various initial water contents. Reaction rate as well as enantioselectivity decreased at high water content. A heteroazeotropic distillation method was applicable to remove the excess water continuously and to work at the optimum reaction conditions.

Original languageEnglish
Pages (from-to)687-690
Number of pages4
JournalBiotechnology Techniques
Issue number9
Publication statusPublished - Sep 1 1995


ASJC Scopus subject areas

  • Biochemistry
  • Applied Microbiology and Biotechnology

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