On-line water removal during enzymatic asymmetric esterification in organic media

L. Gubicza, A. Szakács-Schmidt

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Enantioselective esterification of 2-bromopropionic acid with n-butanol using Candida cylindracea lipase was carried out in n-pentane at various initial water contents. Reaction rate as well as enantioselectivity decreased at high water content. A heteroazeotropic distillation method was applicable to remove the excess water continuously and to work at the optimum reaction conditions.

Original languageEnglish
Pages (from-to)687-690
Number of pages4
JournalBiotechnology Techniques
Volume9
Issue number9
DOIs
Publication statusPublished - Sep 1995

Fingerprint

Water piping systems
Esterification
Water content
1-Butanol
Water
Candida
Enantioselectivity
Lipases
Lipase
Butenes
Distillation
Reaction rates
Acids
2-bromopropionic acid
pentane

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Biochemistry

Cite this

On-line water removal during enzymatic asymmetric esterification in organic media. / Gubicza, L.; Szakács-Schmidt, A.

In: Biotechnology Techniques, Vol. 9, No. 9, 09.1995, p. 687-690.

Research output: Contribution to journalArticle

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