Sajtos nyirokcsomó-gyulladás (pseudotuberculosis) észak-magyarországi juhállományban

Translated title of the contribution: Occurrence of ovine caseous lymphadenitis (pseudotuberculosis) in Northern Hungary

Hajtós István, Makkai István, L. Fodor, L. Makrai

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In June of 2003 caseous lymphadenitis (CL) was diagnosed in a commercial small scale sheep flock in Borsod-Abaúj-Zemplén County (in Northern Hungary). The morbidity rate was 9.5%, because 10 of 105 ewes (2-5 years old) showed clinical symptoms. The other animals, including 2 breeding rams and 28 weaned lambs, in the flock were symptomless. The parotid, retropharyngeal or submandibular lymph nodes were mostly affected (Figures 1, 2, 3). Thick, greyish-green or pale yellowish-green, odourless, purulentnecrotic exudate (Figure 4) were aseptically obtained from the incised lymph nodes for conventional bacteriological examination. The isolated Corynebacterium strains (Figures 5, 6 and 7) were catalase- and urease-positive, fermentative in the OF test. They failed to reduce nitrate, did not liquefy gelatin, produced acid from glucose, but not from mannitol, salicin and trehalose. All isolated strains were toxigenic, because they inhibited the staphylococcal β-haemolysin in the reverse CAMP test (Figure 8). Based upon these characteristics all isolates were identified as nitrate-negative ("ovine/caprine") biotype of Corynebacterium psedotuberculosis. 7 of 10 isolated strains were also characterised by API Coryne System (bioMérieux) and all 7 strains were identified as C. psedotuberculosis (Table). These strains were sensitive to penicillin, erythromycin, doxycycline, Oxytetracycline, cefotaxime, rifampicin and sulfamethoxazol-trimethoprim, but resistant to streptomycin. Surgical, antiseptic and local and parenteral Oxytetracycline treatment of affected lymph nodes was apparently effective, because some weeks later only one relapse could be observed. During the 18 months movement restriction period two new cases of CL were recognized and bacteriologically verified in the flock. These animals were effectively treated in the same manner. According to a questioner survey (in which 50 veterinarians participated), suspected cases of CL were recognized only in three sheep flocks (less than 1.0% of registrated flocks) in Borsod-Abaúj-Zemplén County. This county is the fourth most important sheep-raising area of Hungary. Based upon the data in the literature, the authors emphasized that C. psedotuberculosis is able to cause axillary or inguinal lymphadenitis in humans and the majority of reported human cases were occupational zoonoses.

Original languageHungarian
Pages (from-to)339-347
Number of pages9
JournalMagyar Allatorvosok Lapja
Volume127
Issue number6
Publication statusPublished - 2005

Fingerprint

caseous lymphadenitis
Lymphadenitis
Hungary
Sheep
flocks
sheep
Corynebacterium
Oxytetracycline
Lymph Nodes
lymph nodes
Nitrates
oxytetracycline
Trehalose
Hemolysin Proteins
Trimethoprim
Local Anti-Infective Agents
Cefotaxime
nitrates
Urease
Veterinarians

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Sajtos nyirokcsomó-gyulladás (pseudotuberculosis) észak-magyarországi juhállományban. / István, Hajtós; István, Makkai; Fodor, L.; Makrai, L.

In: Magyar Allatorvosok Lapja, Vol. 127, No. 6, 2005, p. 339-347.

Research output: Contribution to journalArticle

@article{2169b6ca608b45c8be1307da385c03da,
title = "Sajtos nyirokcsom{\'o}-gyullad{\'a}s (pseudotuberculosis) {\'e}szak-magyarorsz{\'a}gi juh{\'a}llom{\'a}nyban",
abstract = "In June of 2003 caseous lymphadenitis (CL) was diagnosed in a commercial small scale sheep flock in Borsod-Aba{\'u}j-Zempl{\'e}n County (in Northern Hungary). The morbidity rate was 9.5{\%}, because 10 of 105 ewes (2-5 years old) showed clinical symptoms. The other animals, including 2 breeding rams and 28 weaned lambs, in the flock were symptomless. The parotid, retropharyngeal or submandibular lymph nodes were mostly affected (Figures 1, 2, 3). Thick, greyish-green or pale yellowish-green, odourless, purulentnecrotic exudate (Figure 4) were aseptically obtained from the incised lymph nodes for conventional bacteriological examination. The isolated Corynebacterium strains (Figures 5, 6 and 7) were catalase- and urease-positive, fermentative in the OF test. They failed to reduce nitrate, did not liquefy gelatin, produced acid from glucose, but not from mannitol, salicin and trehalose. All isolated strains were toxigenic, because they inhibited the staphylococcal β-haemolysin in the reverse CAMP test (Figure 8). Based upon these characteristics all isolates were identified as nitrate-negative ({"}ovine/caprine{"}) biotype of Corynebacterium psedotuberculosis. 7 of 10 isolated strains were also characterised by API Coryne System (bioM{\'e}rieux) and all 7 strains were identified as C. psedotuberculosis (Table). These strains were sensitive to penicillin, erythromycin, doxycycline, Oxytetracycline, cefotaxime, rifampicin and sulfamethoxazol-trimethoprim, but resistant to streptomycin. Surgical, antiseptic and local and parenteral Oxytetracycline treatment of affected lymph nodes was apparently effective, because some weeks later only one relapse could be observed. During the 18 months movement restriction period two new cases of CL were recognized and bacteriologically verified in the flock. These animals were effectively treated in the same manner. According to a questioner survey (in which 50 veterinarians participated), suspected cases of CL were recognized only in three sheep flocks (less than 1.0{\%} of registrated flocks) in Borsod-Aba{\'u}j-Zempl{\'e}n County. This county is the fourth most important sheep-raising area of Hungary. Based upon the data in the literature, the authors emphasized that C. psedotuberculosis is able to cause axillary or inguinal lymphadenitis in humans and the majority of reported human cases were occupational zoonoses.",
author = "Hajt{\'o}s Istv{\'a}n and Makkai Istv{\'a}n and L. Fodor and L. Makrai",
year = "2005",
language = "Hungarian",
volume = "127",
pages = "339--347",
journal = "Magyar Allatorvosok Lapja",
issn = "0025-004X",
publisher = "Magyar Mezogazdasag Ltd",
number = "6",

}

TY - JOUR

T1 - Sajtos nyirokcsomó-gyulladás (pseudotuberculosis) észak-magyarországi juhállományban

AU - István, Hajtós

AU - István, Makkai

AU - Fodor, L.

AU - Makrai, L.

PY - 2005

Y1 - 2005

N2 - In June of 2003 caseous lymphadenitis (CL) was diagnosed in a commercial small scale sheep flock in Borsod-Abaúj-Zemplén County (in Northern Hungary). The morbidity rate was 9.5%, because 10 of 105 ewes (2-5 years old) showed clinical symptoms. The other animals, including 2 breeding rams and 28 weaned lambs, in the flock were symptomless. The parotid, retropharyngeal or submandibular lymph nodes were mostly affected (Figures 1, 2, 3). Thick, greyish-green or pale yellowish-green, odourless, purulentnecrotic exudate (Figure 4) were aseptically obtained from the incised lymph nodes for conventional bacteriological examination. The isolated Corynebacterium strains (Figures 5, 6 and 7) were catalase- and urease-positive, fermentative in the OF test. They failed to reduce nitrate, did not liquefy gelatin, produced acid from glucose, but not from mannitol, salicin and trehalose. All isolated strains were toxigenic, because they inhibited the staphylococcal β-haemolysin in the reverse CAMP test (Figure 8). Based upon these characteristics all isolates were identified as nitrate-negative ("ovine/caprine") biotype of Corynebacterium psedotuberculosis. 7 of 10 isolated strains were also characterised by API Coryne System (bioMérieux) and all 7 strains were identified as C. psedotuberculosis (Table). These strains were sensitive to penicillin, erythromycin, doxycycline, Oxytetracycline, cefotaxime, rifampicin and sulfamethoxazol-trimethoprim, but resistant to streptomycin. Surgical, antiseptic and local and parenteral Oxytetracycline treatment of affected lymph nodes was apparently effective, because some weeks later only one relapse could be observed. During the 18 months movement restriction period two new cases of CL were recognized and bacteriologically verified in the flock. These animals were effectively treated in the same manner. According to a questioner survey (in which 50 veterinarians participated), suspected cases of CL were recognized only in three sheep flocks (less than 1.0% of registrated flocks) in Borsod-Abaúj-Zemplén County. This county is the fourth most important sheep-raising area of Hungary. Based upon the data in the literature, the authors emphasized that C. psedotuberculosis is able to cause axillary or inguinal lymphadenitis in humans and the majority of reported human cases were occupational zoonoses.

AB - In June of 2003 caseous lymphadenitis (CL) was diagnosed in a commercial small scale sheep flock in Borsod-Abaúj-Zemplén County (in Northern Hungary). The morbidity rate was 9.5%, because 10 of 105 ewes (2-5 years old) showed clinical symptoms. The other animals, including 2 breeding rams and 28 weaned lambs, in the flock were symptomless. The parotid, retropharyngeal or submandibular lymph nodes were mostly affected (Figures 1, 2, 3). Thick, greyish-green or pale yellowish-green, odourless, purulentnecrotic exudate (Figure 4) were aseptically obtained from the incised lymph nodes for conventional bacteriological examination. The isolated Corynebacterium strains (Figures 5, 6 and 7) were catalase- and urease-positive, fermentative in the OF test. They failed to reduce nitrate, did not liquefy gelatin, produced acid from glucose, but not from mannitol, salicin and trehalose. All isolated strains were toxigenic, because they inhibited the staphylococcal β-haemolysin in the reverse CAMP test (Figure 8). Based upon these characteristics all isolates were identified as nitrate-negative ("ovine/caprine") biotype of Corynebacterium psedotuberculosis. 7 of 10 isolated strains were also characterised by API Coryne System (bioMérieux) and all 7 strains were identified as C. psedotuberculosis (Table). These strains were sensitive to penicillin, erythromycin, doxycycline, Oxytetracycline, cefotaxime, rifampicin and sulfamethoxazol-trimethoprim, but resistant to streptomycin. Surgical, antiseptic and local and parenteral Oxytetracycline treatment of affected lymph nodes was apparently effective, because some weeks later only one relapse could be observed. During the 18 months movement restriction period two new cases of CL were recognized and bacteriologically verified in the flock. These animals were effectively treated in the same manner. According to a questioner survey (in which 50 veterinarians participated), suspected cases of CL were recognized only in three sheep flocks (less than 1.0% of registrated flocks) in Borsod-Abaúj-Zemplén County. This county is the fourth most important sheep-raising area of Hungary. Based upon the data in the literature, the authors emphasized that C. psedotuberculosis is able to cause axillary or inguinal lymphadenitis in humans and the majority of reported human cases were occupational zoonoses.

UR - http://www.scopus.com/inward/record.url?scp=35948969833&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35948969833&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:35948969833

VL - 127

SP - 339

EP - 347

JO - Magyar Allatorvosok Lapja

JF - Magyar Allatorvosok Lapja

SN - 0025-004X

IS - 6

ER -