Nucleoprotein structure of immediate-early promoters Zp and Rp and of oriLyt of latent Epstein-Barr virus genomes

Hans Helmut Niller, D. Salamon, Jörg Uhlig, Stefanie Ranf, Marcus Granz, Fritz Schwarzmann, Hans Wolf, J. Mináróvits

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Genomic footprints across Rp, Zp, and oriLyt of Epstein-Barr virus (EBV) have been conducted in a panel of latently infected B-cell lines. Close protein-base contacts were found about 360 nucleotides upstream of the Zp initiation site. Gel shifts and transient transfection assays indicated that an Sp1-NF1 locus may serve as a repressive transcriptional element against Zp induction from latent EBV genomes.

Original languageEnglish
Pages (from-to)4113-4118
Number of pages6
JournalJournal of Virology
Volume76
Issue number8
DOIs
Publication statusPublished - 2002

Fingerprint

Human herpesvirus 4
nucleoproteins
Nucleoproteins
Human Herpesvirus 4
promoter regions
Genome
genome
transfection
B-lymphocytes
Transfection
B-Lymphocytes
Nucleotides
Gels
nucleotides
cell lines
gels
genomics
Cell Line
loci
assays

ASJC Scopus subject areas

  • Immunology

Cite this

Nucleoprotein structure of immediate-early promoters Zp and Rp and of oriLyt of latent Epstein-Barr virus genomes. / Niller, Hans Helmut; Salamon, D.; Uhlig, Jörg; Ranf, Stefanie; Granz, Marcus; Schwarzmann, Fritz; Wolf, Hans; Mináróvits, J.

In: Journal of Virology, Vol. 76, No. 8, 2002, p. 4113-4118.

Research output: Contribution to journalArticle

Niller, Hans Helmut ; Salamon, D. ; Uhlig, Jörg ; Ranf, Stefanie ; Granz, Marcus ; Schwarzmann, Fritz ; Wolf, Hans ; Mináróvits, J. / Nucleoprotein structure of immediate-early promoters Zp and Rp and of oriLyt of latent Epstein-Barr virus genomes. In: Journal of Virology. 2002 ; Vol. 76, No. 8. pp. 4113-4118.
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AU - Granz, Marcus

AU - Schwarzmann, Fritz

AU - Wolf, Hans

AU - Mináróvits, J.

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