Novel synthetic approach to the potent germination stimulant strigol and its analogues

I. Kádas, G. Árvai, K. Mikló, G. Horváth, L. Tőke, G. Tóth, A. Szöllösy, M. Bihari

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Strigol (1) is a natural product that triggers suicidal germination of parasitic Striga species. Here we present an improved annulation sequence for the synthesis of the tricyclic moieties of strigol and its analogues. Our approach makes use of the one-pot cyclization of 5-nitro-2-pentanone and cyclopent-2-enone diesters to afford 7-methyl-4-nitro-1-oxo-hydrindene derivatives. Functional group elaboration of these intermediates leads to a series of hydrindene-2-acetic and propionic acids.

Original languageEnglish
Pages (from-to)561-566
Number of pages6
JournalJournal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes
Volume31
Issue number3
Publication statusPublished - 1996

Fingerprint

Striga
Propionic acid
Cyclization
propionic acid
Germination
Acetic acid
Functional groups
functional group
germination
chemical derivatives
Derivatives
synthesis
acid
Propionates
Biological Products
Acetic Acid
strigol
product
cyclodrine
2-pentanone

Keywords

  • Annulation
  • Cyclopent-2-enone derivatives
  • Hydrindene-2-acetic and propionic acids
  • Strigol

ASJC Scopus subject areas

  • Environmental Science(all)
  • Environmental Chemistry
  • Waste Management and Disposal
  • Public Health, Environmental and Occupational Health

Cite this

Novel synthetic approach to the potent germination stimulant strigol and its analogues. / Kádas, I.; Árvai, G.; Mikló, K.; Horváth, G.; Tőke, L.; Tóth, G.; Szöllösy, A.; Bihari, M.

In: Journal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes, Vol. 31, No. 3, 1996, p. 561-566.

Research output: Contribution to journalArticle

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AU - Árvai, G.

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AU - Tőke, L.

AU - Tóth, G.

AU - Szöllösy, A.

AU - Bihari, M.

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