Novel synthetic approach to alkylenedioxy-precocenes

Tibor Timar, Tibor Eszenyi, Peter Sebök, József Jekö

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A novel synthetic route to alkylenedloxy-precocenes 10 having potential precocene antagonist activity - using the reaction of α, ω-dibromoalkanes with 6, 7- or 7, 8-dihydroxy-2,2-dimethyl-4-chromanones 4.5 is described. The structures of intermediate 4-chromanones 6–9 as well as the final regioisomer products 10 were determined by 1H-NMR and MS methods.

Original languageEnglish
Pages (from-to)253-258
Number of pages6
JournalHeterocyclic Communications
Issue number4
Publication statusPublished - Aug 1995


ASJC Scopus subject areas

  • Organic Chemistry

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