Novel reactions of 6,7-dimethoxy-3,4-dihydroisoquinoline and 3,4-dihydro-β-carboline with dipolarophiles

Miklós Nyerges, András Dancsó, I. Bitter, Gábor Blaskó, L. Tőke

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

New reactions of 6,7-dimethoxy-3,4-dihydroisoquinoline and 3,4-dihydro-β-carboline with various electron-deficient olefins are described. 'One-pot' generation and cycloaddition of the 1,3- and 1,4-dipoles formed from these heterocycles with a range of alkene dipolarophiles affords cycloadducts in good yields with high regio- and stereoselectivity.

Original languageEnglish
Pages (from-to)6927-6930
Number of pages4
JournalTetrahedron Letters
Volume46
Issue number40
DOIs
Publication statusPublished - Oct 3 2005

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Carbolines
Alkenes
Stereoselectivity
Regioselectivity
Cycloaddition
Cycloaddition Reaction
Electrons
G 1616

Keywords

  • Azomethine ylides
  • Cycloadditions
  • Indoles
  • Isoquinolines

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Novel reactions of 6,7-dimethoxy-3,4-dihydroisoquinoline and 3,4-dihydro-β-carboline with dipolarophiles. / Nyerges, Miklós; Dancsó, András; Bitter, I.; Blaskó, Gábor; Tőke, L.

In: Tetrahedron Letters, Vol. 46, No. 40, 03.10.2005, p. 6927-6930.

Research output: Contribution to journalArticle

Nyerges, Miklós ; Dancsó, András ; Bitter, I. ; Blaskó, Gábor ; Tőke, L. / Novel reactions of 6,7-dimethoxy-3,4-dihydroisoquinoline and 3,4-dihydro-β-carboline with dipolarophiles. In: Tetrahedron Letters. 2005 ; Vol. 46, No. 40. pp. 6927-6930.
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AU - Blaskó, Gábor

AU - Tőke, L.

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