Novel monoclonal antibodies recognise guinea fowl thrombocytes

Ildikó Bódi, N. Nagy, Lídia Sinka, Botond Zoltán Igyártó, Imre Oláh

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This paper introduces two novel monoclonal antibodies, designated GTr1 and GTr2, which recognise guinea fowl thrombocyte surface antigen(s). The antibodies were tested in embryos and adult birds. GTr1 and GTr2 staining emerged at embryonic days 12 and 7, respectively. After embryonic day 12 there was no difference in staining pattern between the two monoclonal antibodies. The isotype of the antibodies is IgG1. The antibodies did not react with any other haematopoietic cells of guinea fowl, and there was no species cross-reaction with chicken, turkey and quail. The antibodies can be used in interspecies chimeric and parabiotic experiments to identify cells of guinea fowl origin.

Original languageEnglish
Pages (from-to)239-246
Number of pages8
JournalActa Veterinaria Hungarica
Volume57
Issue number2
DOIs
Publication statusPublished - Jun 1 2009

Fingerprint

Guinea
blood platelets
guineafowl
monoclonal antibodies
Blood Platelets
Monoclonal Antibodies
antibodies
Antibodies
Staining and Labeling
Quail
Cross Reactions
surface antigens
Surface Antigens
quails
cross reaction
Birds
Chickens
embryo (animal)
Embryonic Structures
Immunoglobulin G

Keywords

  • Avian
  • Guinea fowl
  • Monoclonal antibodies
  • Thrombocyte

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Novel monoclonal antibodies recognise guinea fowl thrombocytes. / Bódi, Ildikó; Nagy, N.; Sinka, Lídia; Igyártó, Botond Zoltán; Oláh, Imre.

In: Acta Veterinaria Hungarica, Vol. 57, No. 2, 01.06.2009, p. 239-246.

Research output: Contribution to journalArticle

Bódi, Ildikó ; Nagy, N. ; Sinka, Lídia ; Igyártó, Botond Zoltán ; Oláh, Imre. / Novel monoclonal antibodies recognise guinea fowl thrombocytes. In: Acta Veterinaria Hungarica. 2009 ; Vol. 57, No. 2. pp. 239-246.
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