Novel microwave-assisted [3+3] cyclocondensations with 1-cyanomethylene tetrahydroisoquinoline

Péter Nemes, Zoltán Vincze, Barbara Balázs, Gábor Tóth, Pál Scheiber

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

α,β-Unsaturated aldehydes and ketones react with 1-cyanomethylene-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline in microwave-enhanced reactions affording regioselectively 6,7-dihydro-4H-benzo[a]quinolizines and 6,7-dihydro-2H-benzo[a]quinolizines, respectively.

Original languageEnglish
Pages (from-to)250-252
Number of pages3
JournalSynlett
Issue number2
Publication statusPublished - Jan 1 2003

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Keywords

  • Benzo[a]quinolizines
  • Michael additions
  • Microwave heating
  • [3+3] cyclisations
  • β-enaminonitriles

ASJC Scopus subject areas

  • Organic Chemistry

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