Novel, superbase promoted stereoselective rearrangement reactions of chiral oxirane derivatives provided chiral oxetane and azetidine derivatives. An optically active 3,4-disubstituted pyrrolidine was synthetised via catalytic hydrogenolysis of an oxetane derivative followed by ring closure of the formed optically active aminoalcohol.
- Stereoselective rearrangement
ASJC Scopus subject areas
- Biomedical Engineering