Novel methods for the stereoselective synthesis of oxetane, azetidine and pyrrolidine derivatives

F. Faigl, E. Kovács, G. Turczel, L. Hegedus, A. Thurner, F. Farkas, Á Szöllosy

Research output: Contribution to journalArticle


Novel, superbase promoted stereoselective rearrangement reactions of chiral oxirane derivatives provided chiral oxetane and azetidine derivatives. An optically active 3,4-disubstituted pyrrolidine was synthetised via catalytic hydrogenolysis of an oxetane derivative followed by ring closure of the formed optically active aminoalcohol.

Original languageEnglish
Pages (from-to)1366-1369
Number of pages4
JournalIFMBE Proceedings
Publication statusPublished - Nov 9 2011



  • azetidine
  • hydrogenolysis
  • oxetane
  • pyrrolidine
  • Stereoselective rearrangement
  • superbase

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

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