Non-pyramidal cells in the CA3 region of the rat hippocampus: relationships of fine structure, synaptic input and chemical characteristics

Peter Danos, Michael Frotscher, Tamás F. Freund

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The non-pyramidal cells of the hippocampus are heterogeneous with respect to their morphology, peptide content, physiological properties, and postsynaptic targets. Here we demonstrate that the content of peptides (cholecystokinin, somatostatin) and calcium-binding proteins (parvalbumin and calbindin) of non-pyramidal cells is not related to a characteristic fine structure or synaptic input. Varying numbers of GABA-negative and GABA-positive input synapses of non-pyramidal cells indicate that these neurons are differently integrated in inhibitory and disinhibitory circuits.

Original languageEnglish
Pages (from-to)195-202
Number of pages8
JournalBrain research
Volume546
Issue number2
DOIs
Publication statusPublished - Apr 19 1991

Keywords

  • Calbindin
  • Cholecystokinin
  • Hippocampus
  • Inhibition
  • Non-pyramidal cell
  • Parvalbumin
  • Somatostatin
  • γ-Aminobutyric acid

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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