No latent chromosome damage in oxygen-exposed premature neonates

Károly Méhes, Katalin Bajnóczky, Károly Adamovich, Seddiq Khezri, György Kosztolányi

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Abstract

The possible effect of in vivo oxygen exposure on chromosomes was examined in lymphocyte cultures of 12 very-low-birthweight infants on the 1st, 8th, and 16th days of intensive care. No increase of cytogenetic anomalies was seen in untreated and bleomycin-treated cultures. The findings suggest that neonatal oxygen exposure is unlikely to cause latent chromosome damage.

Original languageEnglish
Pages (from-to)40-42
Number of pages3
JournalJournal of Human Genetics
Volume44
Issue number1
DOIs
Publication statusPublished - Feb 8 1999

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Keywords

  • Chromosome instability
  • Neonatal intensive care
  • Oxygen toxicity

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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