No association between maternal recurrent genital herpes in pregnancy and higher risk for congenital abnormalities

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10 Citations (Scopus)

Abstract

Objective. To study the possible links between recurrent symptomatic genital herpes during pregnancy and risk for congenital abnormalities (CAs). Method. The occurrence of prospectively and medically-recorded recurrent genital herpes during pregnancy in the mothers of cases with different congenital abnormalities and in the mothers of matched controls without CAs was compared in the population-based large data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities. Results. Of 22,843 cases with CAs, 59 (0.26%) were born to mothers with recurrent symptomatic genital herpes, while of 38,151 control newborns without CAs, 86 (0.23%) were born to mothers with recurrent genital herpes during the study pregnancy (adjusted OR: 1.1, 95% CI: 0.8-1.6). Pregnant women with clinically recognised recurrent genital herpes in the first trimester of pregnancy are not linked with a higher risk for any CAs. Conclusion. Recurrent genital herpes during pregnancy does not associate with a higher risk of CAs.

Original languageEnglish
Pages (from-to)292-299
Number of pages8
JournalActa Obstetricia et Gynecologica Scandinavica
Volume87
Issue number3
DOIs
Publication statusPublished - 2008

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Herpes Genitalis
High-Risk Pregnancy
Mothers
Pregnancy
First Pregnancy Trimester
Pregnant Women
Newborn Infant

Keywords

  • Case-control design
  • Congenital abnormalities
  • Recurrent genital herpes

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

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title = "No association between maternal recurrent genital herpes in pregnancy and higher risk for congenital abnormalities",
abstract = "Objective. To study the possible links between recurrent symptomatic genital herpes during pregnancy and risk for congenital abnormalities (CAs). Method. The occurrence of prospectively and medically-recorded recurrent genital herpes during pregnancy in the mothers of cases with different congenital abnormalities and in the mothers of matched controls without CAs was compared in the population-based large data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities. Results. Of 22,843 cases with CAs, 59 (0.26{\%}) were born to mothers with recurrent symptomatic genital herpes, while of 38,151 control newborns without CAs, 86 (0.23{\%}) were born to mothers with recurrent genital herpes during the study pregnancy (adjusted OR: 1.1, 95{\%} CI: 0.8-1.6). Pregnant women with clinically recognised recurrent genital herpes in the first trimester of pregnancy are not linked with a higher risk for any CAs. Conclusion. Recurrent genital herpes during pregnancy does not associate with a higher risk of CAs.",
keywords = "Case-control design, Congenital abnormalities, Recurrent genital herpes",
author = "N. {\'A}cs and F. B{\'a}nhidy and E. Puh{\'o} and E. Czeizel",
year = "2008",
doi = "10.1080/00016340801898943",
language = "English",
volume = "87",
pages = "292--299",
journal = "Acta Obstetricia et Gynecologica Scandinavica, Supplement",
issn = "0001-6349",
publisher = "Wiley-Blackwell",
number = "3",

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TY - JOUR

T1 - No association between maternal recurrent genital herpes in pregnancy and higher risk for congenital abnormalities

AU - Ács, N.

AU - Bánhidy, F.

AU - Puhó, E.

AU - Czeizel, E.

PY - 2008

Y1 - 2008

N2 - Objective. To study the possible links between recurrent symptomatic genital herpes during pregnancy and risk for congenital abnormalities (CAs). Method. The occurrence of prospectively and medically-recorded recurrent genital herpes during pregnancy in the mothers of cases with different congenital abnormalities and in the mothers of matched controls without CAs was compared in the population-based large data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities. Results. Of 22,843 cases with CAs, 59 (0.26%) were born to mothers with recurrent symptomatic genital herpes, while of 38,151 control newborns without CAs, 86 (0.23%) were born to mothers with recurrent genital herpes during the study pregnancy (adjusted OR: 1.1, 95% CI: 0.8-1.6). Pregnant women with clinically recognised recurrent genital herpes in the first trimester of pregnancy are not linked with a higher risk for any CAs. Conclusion. Recurrent genital herpes during pregnancy does not associate with a higher risk of CAs.

AB - Objective. To study the possible links between recurrent symptomatic genital herpes during pregnancy and risk for congenital abnormalities (CAs). Method. The occurrence of prospectively and medically-recorded recurrent genital herpes during pregnancy in the mothers of cases with different congenital abnormalities and in the mothers of matched controls without CAs was compared in the population-based large data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities. Results. Of 22,843 cases with CAs, 59 (0.26%) were born to mothers with recurrent symptomatic genital herpes, while of 38,151 control newborns without CAs, 86 (0.23%) were born to mothers with recurrent genital herpes during the study pregnancy (adjusted OR: 1.1, 95% CI: 0.8-1.6). Pregnant women with clinically recognised recurrent genital herpes in the first trimester of pregnancy are not linked with a higher risk for any CAs. Conclusion. Recurrent genital herpes during pregnancy does not associate with a higher risk of CAs.

KW - Case-control design

KW - Congenital abnormalities

KW - Recurrent genital herpes

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JO - Acta Obstetricia et Gynecologica Scandinavica, Supplement

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