NMR study of 6-azabicyclo[3.2.1]octene derivatives, By-products of catharanthine synthesis

E. Gács-Baitz, Hedvig Bölcskei, Csaba Szántay

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2 Citations (Scopus)

Abstract

The structures and stereochemistries of several 6-azabicyclo[3.2.1]octene derivatives, obtained by rearrangement reactions of the catharanthine synthesis, were determined by various NMR methods. Long-range 13C-1H coupling constants were measured by selective two-dimensional INEPT experiments. The dependence of 3J(C, H) and 2J(C, H) coupling constants on the dihedral angles and on the position of an electronegative substituent along the coupling path was studied.

Original languageEnglish
Pages (from-to)213-218
Number of pages6
JournalJournal of the Chemical Society, Perkin Transactions 2
Issue number2
DOIs
Publication statusPublished - 1994

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Stereochemistry
Dihedral angle
Byproducts
Nuclear magnetic resonance
Derivatives
Experiments
catharanthine

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

NMR study of 6-azabicyclo[3.2.1]octene derivatives, By-products of catharanthine synthesis. / Gács-Baitz, E.; Bölcskei, Hedvig; Szántay, Csaba.

In: Journal of the Chemical Society, Perkin Transactions 2, No. 2, 1994, p. 213-218.

Research output: Contribution to journalArticle

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