The structures and stereochemistries of several 6-azabicyclo[3.2.1]octene derivatives, obtained by rearrangement reactions of the catharanthine synthesis, were determined by various NMR methods. Long-range 13C-1H coupling constants were measured by selective two-dimensional INEPT experiments. The dependence of 3J(C, H) and 2J(C, H) coupling constants on the dihedral angles and on the position of an electronegative substituent along the coupling path was studied.
|Number of pages||6|
|Journal||Journal of the Chemical Society, Perkin Transactions 2|
|Publication status||Published - Jan 1 1994|
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