This review is concerning with the endothel derived relaxing factor (EDRF) discovered in 1980 and identified as NO in 1987 in the function and activities of the gastrointestinal tract and the liver. It is of importance, that NO seems to basic mediator of the so called nonadrenerg-noncholinerg inhibitory innervation of the bowel, and also takes part in the regulation of mucosal blood supply and secretory function. In portal hypertension elevated cGMP is found in the urine, as evidence of increased nitrogen oxide synthase (NOS) activity. NO may act both as hepatoprotective and cytotoxic factor in the free radical reactions of several liver disease.
|Translated title of the contribution||Nitrogen monoxide (NO) in the function of the gastrointestinal tract and the liver|
|Number of pages||5|
|Publication status||Published - Jun 15 1997|
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