Nitrogen bridgehead compounds. Part 83 . Synthesis and ring transformation of 6‐methyl‐4‐oxo‐4H‐pyrido[1,2‐a]pyrimidine‐3‐acrylates

I. Hermecz, Agnes Horváth

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The thermal ring transformation of 2‐substituted 4‐oxo‐4H‐pyrido[1,2‐a]pyrimidine‐3‐acrylates gave 2‐substituted 1,8‐naphthyridine‐3‐acrylates, pyrano‐1,8‐naphthyridines and anthyridine, depending upon the nature of the 2‐substituent. A longer reaction period and a higher reaction temperature favored the formation of tricyclic products from 1,8‐naphthyridine‐3‐acrylate after isomerization of the side‐chain at position 3. The products were characterized by means of uv, ir and 1H nmr spectroscopy.

Original languageEnglish
Pages (from-to)559-564
Number of pages6
JournalJournal of Heterocyclic Chemistry
Volume29
Issue number2
DOIs
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Organic Chemistry

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