Nitrogen bridgehead compounds. Part 4. 1 → 3N → C-acyl migration. Part 2

I. Hermecz, Zoltán Mészáros, Lelle Vasvári-Debreczy, Ágnes Horváth, Gábor Horváth, Mariann Pongor-Csákvári

Research output: Contribution to journalArticle

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Abstract

Ring closure of 2-substituted 3-(2-pyridylamino)acrylates (1) in phosphoryl chloride-polyphosphoric acid gives pyrido[1,2-a]pyrimidines (2), whereas (6-substituted 2-pyridyl) derivatives in Dowtherm A afford pyrido[1,2-a]- pyrimidines (2) and 1,8-naphthyridines (3). The 6-substituted pyrido[1,2-a]pyrimidines (2) can be converted thermally into 1,8-naphthyridines (3) by 1 → 3 N → C-acyl migration. Similar acyl migrations can be observed in other such systems.

Original languageEnglish
Pages (from-to)789-795
Number of pages7
JournalJournal of the Chemical Society, Perkin Transactions 1
Issue number7
Publication statusPublished - 1977

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Nitrogen Compounds
Pyrimidines
Naphthyridines
Acrylates
Derivatives

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Hermecz, I., Mészáros, Z., Vasvári-Debreczy, L., Horváth, Á., Horváth, G., & Pongor-Csákvári, M. (1977). Nitrogen bridgehead compounds. Part 4. 1 → 3N → C-acyl migration. Part 2. Journal of the Chemical Society, Perkin Transactions 1, (7), 789-795.

Nitrogen bridgehead compounds. Part 4. 1 → 3N → C-acyl migration. Part 2. / Hermecz, I.; Mészáros, Zoltán; Vasvári-Debreczy, Lelle; Horváth, Ágnes; Horváth, Gábor; Pongor-Csákvári, Mariann.

In: Journal of the Chemical Society, Perkin Transactions 1, No. 7, 1977, p. 789-795.

Research output: Contribution to journalArticle

Hermecz, I, Mészáros, Z, Vasvári-Debreczy, L, Horváth, Á, Horváth, G & Pongor-Csákvári, M 1977, 'Nitrogen bridgehead compounds. Part 4. 1 → 3N → C-acyl migration. Part 2', Journal of the Chemical Society, Perkin Transactions 1, no. 7, pp. 789-795.
Hermecz I, Mészáros Z, Vasvári-Debreczy L, Horváth Á, Horváth G, Pongor-Csákvári M. Nitrogen bridgehead compounds. Part 4. 1 → 3N → C-acyl migration. Part 2. Journal of the Chemical Society, Perkin Transactions 1. 1977;(7):789-795.
Hermecz, I. ; Mészáros, Zoltán ; Vasvári-Debreczy, Lelle ; Horváth, Ágnes ; Horváth, Gábor ; Pongor-Csákvári, Mariann. / Nitrogen bridgehead compounds. Part 4. 1 → 3N → C-acyl migration. Part 2. In: Journal of the Chemical Society, Perkin Transactions 1. 1977 ; No. 7. pp. 789-795.
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AU - Pongor-Csákvári, Mariann

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