Nitrogen bridgehead compounds. Part 19. Synthesis of polymethylenepyrimidin‐4‐ones

J. Kökösi, G. Szász, I. Hermecz, Zoltán Mészáros, Marianne Csákvári‐Pongor, Gábor Tóth

Research output: Contribution to journalArticle

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Abstract

Reaction of five‐, six‐, seven‐, and eight‐membered cyclic amidines (1 n = 0‐3) with diethyl ethoxy‐methylenemalonate (2) yields isomeric 2,3‐polymethylene‐4(3H]‐ and 1,2‐polymethytlene‐4(1H)‐pyrimidinones (3 and 4) respectively, n = 0‐3). With 2‐aminopyrroline the isomer ratio was dependent upon the reaction conditions. The structure of the isomers 3 and 4 was studied by uv, ir and 1H‐nmr spectroscopy. Both isomers contain an active methylene group which can be deuterated. Deuteration was investigated with 1H‐nmr spectroscopy.

Original languageEnglish
Pages (from-to)909-912
Number of pages4
JournalJournal of Heterocyclic Chemistry
Volume19
Issue number4
DOIs
Publication statusPublished - 1982

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Nitrogen Compounds
Isomers
Pyrimidinones
Amidines
Spectroscopy

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Nitrogen bridgehead compounds. Part 19. Synthesis of polymethylenepyrimidin‐4‐ones. / Kökösi, J.; Szász, G.; Hermecz, I.; Mészáros, Zoltán; Csákvári‐Pongor, Marianne; Tóth, Gábor.

In: Journal of Heterocyclic Chemistry, Vol. 19, No. 4, 1982, p. 909-912.

Research output: Contribution to journalArticle

Kökösi, J. ; Szász, G. ; Hermecz, I. ; Mészáros, Zoltán ; Csákvári‐Pongor, Marianne ; Tóth, Gábor. / Nitrogen bridgehead compounds. Part 19. Synthesis of polymethylenepyrimidin‐4‐ones. In: Journal of Heterocyclic Chemistry. 1982 ; Vol. 19, No. 4. pp. 909-912.
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AU - Csákvári‐Pongor, Marianne

AU - Tóth, Gábor

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