New thermogravimetric protocol for the investigation of normal and damaged human hyaline cartilage

G. Sohár, E. Pallagi, P. Szabó-Révész, K. Tóth

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Osteoarthritis, although classically conceived of as a degenerative consequence of aging, is a disease with an increasingly well-characterized molecular pathophysiology. Pathologic changes in cartilage composition and molecular organization, as well as elevated water content, alter the exquisite balance of biomechanical properties. Much of what is known about changes in the extracellular matrix in osteoarthritis comes from animal models. Previously, thermogravimetric methods have not been used for compositional thermoanalytical study of normal and degenerative human hyaline cartilage. For this reason the research group established a sufficient new thermogravimetric protocol, which proved water content elevation contributing to disease progression.

Original languageEnglish
Pages (from-to)853-856
Number of pages4
JournalJournal of Thermal Analysis and Calorimetry
Volume89
Issue number3
DOIs
Publication statusPublished - Sep 1 2007

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Keywords

  • Activation energy
  • Human hyaline cartilage
  • Osteoarthritis
  • Thermogravimetry

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

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