New technique in optical resolutions

Mária Ács, András avik, Elemér Fogassy, Zsolt Böcskei

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The present paper illustrates the development of an advanced technique in optical resolution. Both of the amphetamine enantiomers can be obtained by a two‐step distillation in nearly quantitative yield without any loss of the resolving agent. It is proved that the second‐order interactions (H‐bond) are sufficient for separation of enantiomers by distillation. © 1994 Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)314-320
Number of pages7
JournalChirality
Volume6
Issue number4
DOIs
Publication statusPublished - 1994

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Keywords

  • amphetamine
  • clathrate
  • distillation method
  • optical activation of bases

ASJC Scopus subject areas

  • Analytical Chemistry
  • Catalysis
  • Pharmacology
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

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