HCG follow up was analyzed from 400 patients treated at New England Trophoblastic Disease Center (NETDC) with either complete or partial hydatidiform mole. Although prolonged serum human chorionic gonadotropin (hCG) monitoring is advised to ensure that relapse is detected, patients may not complete the entire recommended interval of follow up. This study was undertaken to analyze how often patients with molar pregnancy do not complete their entire follow up and to determine the minimal interval of hCG monitoring required for safe screening of relapse. 400 randomly selected patients with molar pregnancy were analyzed regarding the serum hCG levels following molar evacuation. Patients who developed persistent gestational trophoblastic tumor (GTT) before serum hCG had become undetectable were excluded from further analysis (n=67; 17 %). Of the 333 uncomplicated cases, 211 (63 %) completed the recommended hCG follow up protocol. 320 patients achieved at least one negative serum hCG level, and none had any evidence of relapse of persistent GTT. Data indicate that relapse of uncomplicated molar pregnancies is unlikely after undetectable hCG levels are attained. Further follow up may not be indicated.
|Translated title of the contribution||New suggestion to the current practice of hCG follow up after molar evacuation|
|Number of pages||5|
|Journal||Magyar Noorvosok Lapja|
|Publication status||Published - Oct 20 2003|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology