Uj stratégia a pajzsmirigyfunkció diagnosztikájában.

Translated title of the contribution: New strategy for thyroid function testing

E. Toldy, Z. Löcsei, S. Héber, K. Gundy, L. Varga, G. Kovács

Research output: Contribution to journalArticle

Abstract

The authors used a new protocol, based upon a supersensitive TSH assay, to examine the thyroid status of 1720 patients. Based upon the serum hormone levels, the patients were divided into different clinical groups. The biochemical relationship between the different hormone levels, and the rate of occurrence of various thyroid diseases were studied. 76.1% of the new patients hadn't received any previous treatment. 15.5% of those patients who had received treatment had hyperthyroidism, while 8.4% of those had hypothyroidism. 76% of the new patients, 38.3% of those who had hyperthyroidism, and only 29.7% of those who had hypothyroidism, were euthyroid. Undetectable TSH levels (< 0.03 mU/L) where observed in 51.8% of the new hyperthyroid patients, and in 33.8% of those who had subclinical hyperthyroidism. Similar results were obtained with those who had been previously treated for hyperthyroidism. The new protocol has the following advantages: it's more convenient to the patients, it's quick, it's economical. With this method it is possible to reduce the assays per patient by 31%. The algorithm was supplemented with results of free hormone levels. By doing this the authors were able to measure free-T4 and T3 hormone levels of 150 more patients. According to the authors, the free-T4 test is more informative than the free-T4-index, especially in the border-line cases and in treated hyperthyroidism. Primarily the free-T3 test is most necessary when examining patients treated with methimasol.

Original languageHungarian
Pages (from-to)1571-1576
Number of pages6
JournalOrvosi Hetilap
Volume134
Issue number29
Publication statusPublished - Jul 18 1993

Fingerprint

Thyroid Gland
Hyperthyroidism
Hormones
Hypothyroidism
Thyroid Diseases
Therapeutics
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Toldy, E., Löcsei, Z., Héber, S., Gundy, K., Varga, L., & Kovács, G. (1993). Uj stratégia a pajzsmirigyfunkció diagnosztikájában. Orvosi Hetilap, 134(29), 1571-1576.

Uj stratégia a pajzsmirigyfunkció diagnosztikájában. / Toldy, E.; Löcsei, Z.; Héber, S.; Gundy, K.; Varga, L.; Kovács, G.

In: Orvosi Hetilap, Vol. 134, No. 29, 18.07.1993, p. 1571-1576.

Research output: Contribution to journalArticle

Toldy, E, Löcsei, Z, Héber, S, Gundy, K, Varga, L & Kovács, G 1993, 'Uj stratégia a pajzsmirigyfunkció diagnosztikájában.', Orvosi Hetilap, vol. 134, no. 29, pp. 1571-1576.
Toldy E, Löcsei Z, Héber S, Gundy K, Varga L, Kovács G. Uj stratégia a pajzsmirigyfunkció diagnosztikájában. Orvosi Hetilap. 1993 Jul 18;134(29):1571-1576.
Toldy, E. ; Löcsei, Z. ; Héber, S. ; Gundy, K. ; Varga, L. ; Kovács, G. / Uj stratégia a pajzsmirigyfunkció diagnosztikájában. In: Orvosi Hetilap. 1993 ; Vol. 134, No. 29. pp. 1571-1576.
@article{54766fb790894ad68b467e7a8c5b1e80,
title = "Uj strat{\'e}gia a pajzsmirigyfunkci{\'o} diagnosztik{\'a}j{\'a}ban.",
abstract = "The authors used a new protocol, based upon a supersensitive TSH assay, to examine the thyroid status of 1720 patients. Based upon the serum hormone levels, the patients were divided into different clinical groups. The biochemical relationship between the different hormone levels, and the rate of occurrence of various thyroid diseases were studied. 76.1{\%} of the new patients hadn't received any previous treatment. 15.5{\%} of those patients who had received treatment had hyperthyroidism, while 8.4{\%} of those had hypothyroidism. 76{\%} of the new patients, 38.3{\%} of those who had hyperthyroidism, and only 29.7{\%} of those who had hypothyroidism, were euthyroid. Undetectable TSH levels (< 0.03 mU/L) where observed in 51.8{\%} of the new hyperthyroid patients, and in 33.8{\%} of those who had subclinical hyperthyroidism. Similar results were obtained with those who had been previously treated for hyperthyroidism. The new protocol has the following advantages: it's more convenient to the patients, it's quick, it's economical. With this method it is possible to reduce the assays per patient by 31{\%}. The algorithm was supplemented with results of free hormone levels. By doing this the authors were able to measure free-T4 and T3 hormone levels of 150 more patients. According to the authors, the free-T4 test is more informative than the free-T4-index, especially in the border-line cases and in treated hyperthyroidism. Primarily the free-T3 test is most necessary when examining patients treated with methimasol.",
author = "E. Toldy and Z. L{\"o}csei and S. H{\'e}ber and K. Gundy and L. Varga and G. Kov{\'a}cs",
year = "1993",
month = "7",
day = "18",
language = "Hungarian",
volume = "134",
pages = "1571--1576",
journal = "Orvosi Hetilap",
issn = "0030-6002",
publisher = "Akademiai Kiado",
number = "29",

}

TY - JOUR

T1 - Uj stratégia a pajzsmirigyfunkció diagnosztikájában.

AU - Toldy, E.

AU - Löcsei, Z.

AU - Héber, S.

AU - Gundy, K.

AU - Varga, L.

AU - Kovács, G.

PY - 1993/7/18

Y1 - 1993/7/18

N2 - The authors used a new protocol, based upon a supersensitive TSH assay, to examine the thyroid status of 1720 patients. Based upon the serum hormone levels, the patients were divided into different clinical groups. The biochemical relationship between the different hormone levels, and the rate of occurrence of various thyroid diseases were studied. 76.1% of the new patients hadn't received any previous treatment. 15.5% of those patients who had received treatment had hyperthyroidism, while 8.4% of those had hypothyroidism. 76% of the new patients, 38.3% of those who had hyperthyroidism, and only 29.7% of those who had hypothyroidism, were euthyroid. Undetectable TSH levels (< 0.03 mU/L) where observed in 51.8% of the new hyperthyroid patients, and in 33.8% of those who had subclinical hyperthyroidism. Similar results were obtained with those who had been previously treated for hyperthyroidism. The new protocol has the following advantages: it's more convenient to the patients, it's quick, it's economical. With this method it is possible to reduce the assays per patient by 31%. The algorithm was supplemented with results of free hormone levels. By doing this the authors were able to measure free-T4 and T3 hormone levels of 150 more patients. According to the authors, the free-T4 test is more informative than the free-T4-index, especially in the border-line cases and in treated hyperthyroidism. Primarily the free-T3 test is most necessary when examining patients treated with methimasol.

AB - The authors used a new protocol, based upon a supersensitive TSH assay, to examine the thyroid status of 1720 patients. Based upon the serum hormone levels, the patients were divided into different clinical groups. The biochemical relationship between the different hormone levels, and the rate of occurrence of various thyroid diseases were studied. 76.1% of the new patients hadn't received any previous treatment. 15.5% of those patients who had received treatment had hyperthyroidism, while 8.4% of those had hypothyroidism. 76% of the new patients, 38.3% of those who had hyperthyroidism, and only 29.7% of those who had hypothyroidism, were euthyroid. Undetectable TSH levels (< 0.03 mU/L) where observed in 51.8% of the new hyperthyroid patients, and in 33.8% of those who had subclinical hyperthyroidism. Similar results were obtained with those who had been previously treated for hyperthyroidism. The new protocol has the following advantages: it's more convenient to the patients, it's quick, it's economical. With this method it is possible to reduce the assays per patient by 31%. The algorithm was supplemented with results of free hormone levels. By doing this the authors were able to measure free-T4 and T3 hormone levels of 150 more patients. According to the authors, the free-T4 test is more informative than the free-T4-index, especially in the border-line cases and in treated hyperthyroidism. Primarily the free-T3 test is most necessary when examining patients treated with methimasol.

UR - http://www.scopus.com/inward/record.url?scp=0027919813&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027919813&partnerID=8YFLogxK

M3 - Article

C2 - 8101646

AN - SCOPUS:0027919813

VL - 134

SP - 1571

EP - 1576

JO - Orvosi Hetilap

JF - Orvosi Hetilap

SN - 0030-6002

IS - 29

ER -