New prognostic score for the prediction of 30-day outcome in spontaneous supratentorial cerebral haemorrhage

Rita Szepesi, Ibolya Katalin Széll, T. Hortobágyi, László Kardos, Katalin Nagy, Levente István Lánczi, Ervin Berényi, D. Bereczki, L. Csiba

Research output: Contribution to journalArticle

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Abstract

Aims. The purpose of the present study was to evaluate predictors of outcome in primary supratentorial cerebral haemorrhage. Furthermore, we aimed to develop a prognostic model to predict 30-day fatality. Methods. We retrospectively analyzed a database of 156 patients with spontaneous supratentorial haemorrhage to explore the relationship between clinical and CT characteristics and fatal outcome within 30 days using multiple logistic regression analysis. The analyzed factors included volumetric data assessed by neuropathological and CT volumetry. A second CT scan in survivors or neuropathological ABC/2 volumetry in nonsurvivors was used along with the baseline CT to assess the growth index of haematoma. Results. Systolic blood pressure, serum potassium and glucose levels, platelet count, absolute and relative haematoma volumes, and presence and size of intraventricular haemorrhage statistically significantly predicted the fatal outcome within 30 days. Based on our results we formulated a six-factor scoring algorithm named SUSPEKT to predict outcome. Conclusions. After validation the SUSPEKT score may be applicable in general clinical practice for early patient selection to optimize individual management or for assessment of eligibility for treatment trials.

Original languageEnglish
Article number961085
JournalBioMed Research International
Volume2015
DOIs
Publication statusPublished - Jan 8 2015

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Fatal Outcome
Computerized tomography
Blood pressure
Cerebral Hemorrhage
Platelets
Regression analysis
Hematoma
Logistics
Potassium
Hemorrhage
Blood Pressure
Glucose
Platelet Count
General Practice
Patient Selection
Survivors
Logistic Models
Regression Analysis
Databases
Growth

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

New prognostic score for the prediction of 30-day outcome in spontaneous supratentorial cerebral haemorrhage. / Szepesi, Rita; Széll, Ibolya Katalin; Hortobágyi, T.; Kardos, László; Nagy, Katalin; Lánczi, Levente István; Berényi, Ervin; Bereczki, D.; Csiba, L.

In: BioMed Research International, Vol. 2015, 961085, 08.01.2015.

Research output: Contribution to journalArticle

Szepesi, Rita ; Széll, Ibolya Katalin ; Hortobágyi, T. ; Kardos, László ; Nagy, Katalin ; Lánczi, Levente István ; Berényi, Ervin ; Bereczki, D. ; Csiba, L. / New prognostic score for the prediction of 30-day outcome in spontaneous supratentorial cerebral haemorrhage. In: BioMed Research International. 2015 ; Vol. 2015.
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