A human magnezium- es nyomelemhiany oralis potlasanak uj anyagai: A fem poligalakturonatok

Translated title of the contribution: New products: Metal polygalacturonates for the oral treatment of magnesium and trace metal deficiency in humans

B. Lakatos, K. Szentmihalyi, Z. Sandor, P. Vinkler

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Several substances, such as inorganic salts or minerals, metal complexes of monomer organic compounds, metal biopolymer colloids are available for the treatment of essential macro (e.g. Mg) meso (Fe) and micro (e.g. Cu, Zn, Mn, Co) element deficiency in humans. The low absorbability and bioavailability and adverse side effects of majority of the mentioned substances were eliminated by oral application of new products: metal polygalacturonates. Metal polygalacturonates could be prepared from pectin - a component of higher order plants - with the addition of essential metals. We have obtained metal polygalacturonates in the form of polynuclear complexes of various compositions as neutral, basic or mixed anion compounds. The medium molecular massess and stability constans further the high ionselectivity values of metal polygalacturonates make these products suitable for high absorption and beneficial bioavailability without side effects. Our preparations contain synergetic metals (e.g. Cu, Zn, Mn, Co) and vitamins (e.g. B1, B6, B9) for the treatment of single metal deficiencies (e.g. Mg) or metal deficiency diseases (e.g. anaemia, heart arrhythmia). These preparations: Magnacomp (Mg, vitamin B1, B6, arginine), Multicomp (Mg, Fe, Cu, Zn, Mn) and Ferrocomp (Fe, Cu, Zn, Mn, Co, vitamin C and B9) are on the market in the Hungary as natural medicinal products. Toxicological, absorptivity and bioavailability investigations of the products have been performed.

Original languageHungarian
Pages (from-to)534-540
Number of pages7
JournalGyogyszereszet
Volume41
Issue number9
Publication statusPublished - 1997

Fingerprint

Magnesium
Metals
Biological Availability
Thiamine
Deficiency Diseases
Biopolymers
Vitamin B 6
Hungary
Coordination Complexes
Colloids
Folic Acid
Toxicology
Ascorbic Acid
Anions
Minerals
Arginine
Cardiac Arrhythmias
Anemia
Salts

ASJC Scopus subject areas

  • Pharmacology

Cite this

A human magnezium- es nyomelemhiany oralis potlasanak uj anyagai : A fem poligalakturonatok. / Lakatos, B.; Szentmihalyi, K.; Sandor, Z.; Vinkler, P.

In: Gyogyszereszet, Vol. 41, No. 9, 1997, p. 534-540.

Research output: Contribution to journalArticle

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