New pathways towards pyridazino-fused ring systems

P. Mátyus, Bert U W Maes, Z. Riedl, G. Hajós, Guy L F Lemière, P. Tapolcsányi, Katrien Monsieurs, Olivér Éliás, Roger A. Dommisse, Gábor Krajsovszky

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Novel, efficient synthetic pathways were developed for the synthesis of a variety of pyridazino-fused polycyclic ring systems not easily accessible by other routes. The strategy is based on the sequential or one-pot combinations of a palladium catalyzed C-C bond forming process (Suzuki or Heck-type reaction) and a C-X (X = N, O) or another C-C bond forming reaction (for C-X: nucleophilic substitution, condensation, lactonization, nitrene C-H insertion, Buchwald-Hartwig animation; for C-C: Pschorr reaction, Heck-type reaction). Some of these methodologies have also been extended to the preparation of several diazino-fused ring systems.

Original languageEnglish
Pages (from-to)1123-1139
Number of pages17
JournalSynlett
Issue number7
Publication statusPublished - Jun 3 2004

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Palladium
Animation
Condensation
Substitution reactions
phenylnitrene

Keywords

  • Diazino-fused ring systems
  • Palladium-catalyzed reaction
  • Pyridazine
  • Pyridazino-fused ring systems

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Mátyus, P., Maes, B. U. W., Riedl, Z., Hajós, G., Lemière, G. L. F., Tapolcsányi, P., ... Krajsovszky, G. (2004). New pathways towards pyridazino-fused ring systems. Synlett, (7), 1123-1139.

New pathways towards pyridazino-fused ring systems. / Mátyus, P.; Maes, Bert U W; Riedl, Z.; Hajós, G.; Lemière, Guy L F; Tapolcsányi, P.; Monsieurs, Katrien; Éliás, Olivér; Dommisse, Roger A.; Krajsovszky, Gábor.

In: Synlett, No. 7, 03.06.2004, p. 1123-1139.

Research output: Contribution to journalArticle

Mátyus, P, Maes, BUW, Riedl, Z, Hajós, G, Lemière, GLF, Tapolcsányi, P, Monsieurs, K, Éliás, O, Dommisse, RA & Krajsovszky, G 2004, 'New pathways towards pyridazino-fused ring systems', Synlett, no. 7, pp. 1123-1139.
Mátyus, P. ; Maes, Bert U W ; Riedl, Z. ; Hajós, G. ; Lemière, Guy L F ; Tapolcsányi, P. ; Monsieurs, Katrien ; Éliás, Olivér ; Dommisse, Roger A. ; Krajsovszky, Gábor. / New pathways towards pyridazino-fused ring systems. In: Synlett. 2004 ; No. 7. pp. 1123-1139.
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