Új módszerek a prosztatadaganatok sugárkezelé sében

dinamikus ívbesugárzás és kilovoltos .,cone-beam" komputertomográfiás ellenorzés

Translated title of the contribution: New methods in the treatment of localized prostate cancer: Usage of dynamic arc therapy and kV cone-beam CT positioning

Szabolcs Szappanos, Róbert Farkas, Zoltán Locsei, Zoltán László, Judit Kalincsák, S. Bellyei, Zsolt Sebestyén, László Csapó, Klára Sebestyén, Judit Halász, Zoltán Musch, Tamás Beöthe, László Farkas, László Mangel

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Introduction: Prostate cancer is a common disease among elderly male patients in developed countries. In addition to prostatectomy, definitive irradiation plays an increasing role in the treatment of localized disease. Aim: The authors wanted to share their experience obtained with the use of the Novalis TX linear accelerator for the application of dose-escalation, dynamic, intensity modulated arc therapy with the routine usage of cone-beam computer tomography based or image guided radiotherapy in patients with prostate cancer. Method: Between 2011, December and 2013, February the authors performed 102 treatments. In 10 low risk and 10 high risk prostate cancer patients (median age: 72.5 years) three-dimensional conformal plans with the same target volume coverage were created and tolerance doses of organs at risk (OAR) were compared. Results: Compared to three-dimensional conformal techniques, intensity modulated arc therapy treatments produced a significantly lower dose at organ at risk that led to a more favorable early toxicity rate. Conclusions: The intensity modulated arc therapy with image guided radiotherapy proved to be a safe standard treatment mode in the daily routine in the institute of the authors. Late toxicity and local control rates need to be further examined.

Original languageHungarian
Pages (from-to)1265-1272
Number of pages8
JournalOrvosi Hetilap
Volume155
Issue number32
DOIs
Publication statusPublished - Aug 1 2014

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Cone-Beam Computed Tomography
Intensity-Modulated Radiotherapy
Prostatic Neoplasms
Image-Guided Radiotherapy
Organs at Risk
Particle Accelerators
Therapeutics
Prostatectomy
Developed Countries
Tomography

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Új módszerek a prosztatadaganatok sugárkezelé sében : dinamikus ívbesugárzás és kilovoltos .,cone-beam" komputertomográfiás ellenorzés. / Szappanos, Szabolcs; Farkas, Róbert; Locsei, Zoltán; László, Zoltán; Kalincsák, Judit; Bellyei, S.; Sebestyén, Zsolt; Csapó, László; Sebestyén, Klára; Halász, Judit; Musch, Zoltán; Beöthe, Tamás; Farkas, László; Mangel, László.

In: Orvosi Hetilap, Vol. 155, No. 32, 01.08.2014, p. 1265-1272.

Research output: Contribution to journalArticle

Szappanos, S, Farkas, R, Locsei, Z, László, Z, Kalincsák, J, Bellyei, S, Sebestyén, Z, Csapó, L, Sebestyén, K, Halász, J, Musch, Z, Beöthe, T, Farkas, L & Mangel, L 2014, 'Új módszerek a prosztatadaganatok sugárkezelé sében: dinamikus ívbesugárzás és kilovoltos .,cone-beam" komputertomográfiás ellenorzés', Orvosi Hetilap, vol. 155, no. 32, pp. 1265-1272. https://doi.org/10.1556/OH.2014.29883
Szappanos, Szabolcs ; Farkas, Róbert ; Locsei, Zoltán ; László, Zoltán ; Kalincsák, Judit ; Bellyei, S. ; Sebestyén, Zsolt ; Csapó, László ; Sebestyén, Klára ; Halász, Judit ; Musch, Zoltán ; Beöthe, Tamás ; Farkas, László ; Mangel, László. / Új módszerek a prosztatadaganatok sugárkezelé sében : dinamikus ívbesugárzás és kilovoltos .,cone-beam" komputertomográfiás ellenorzés. In: Orvosi Hetilap. 2014 ; Vol. 155, No. 32. pp. 1265-1272.
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T2 - dinamikus ívbesugárzás és kilovoltos .,cone-beam" komputertomográfiás ellenorzés

AU - Szappanos, Szabolcs

AU - Farkas, Róbert

AU - Locsei, Zoltán

AU - László, Zoltán

AU - Kalincsák, Judit

AU - Bellyei, S.

AU - Sebestyén, Zsolt

AU - Csapó, László

AU - Sebestyén, Klára

AU - Halász, Judit

AU - Musch, Zoltán

AU - Beöthe, Tamás

AU - Farkas, László

AU - Mangel, László

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Y1 - 2014/8/1

N2 - Introduction: Prostate cancer is a common disease among elderly male patients in developed countries. In addition to prostatectomy, definitive irradiation plays an increasing role in the treatment of localized disease. Aim: The authors wanted to share their experience obtained with the use of the Novalis TX linear accelerator for the application of dose-escalation, dynamic, intensity modulated arc therapy with the routine usage of cone-beam computer tomography based or image guided radiotherapy in patients with prostate cancer. Method: Between 2011, December and 2013, February the authors performed 102 treatments. In 10 low risk and 10 high risk prostate cancer patients (median age: 72.5 years) three-dimensional conformal plans with the same target volume coverage were created and tolerance doses of organs at risk (OAR) were compared. Results: Compared to three-dimensional conformal techniques, intensity modulated arc therapy treatments produced a significantly lower dose at organ at risk that led to a more favorable early toxicity rate. Conclusions: The intensity modulated arc therapy with image guided radiotherapy proved to be a safe standard treatment mode in the daily routine in the institute of the authors. Late toxicity and local control rates need to be further examined.

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