New MEMS tweezers for the viscoelastic characterization of soft materials at the microscale

Paolo Di Giamberardino, Alvise Bagolini, Pierluigi Bellutti, I. Rudas, Matteo Verotti, Fabio Botta, Nicola P. Belfiore

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

As many studies show, there is a relation between the tissue's mechanical characteristics and some specific diseases. Knowing this relationship would help early diagnosis or microsurgery. In this paper, a new method for measuring the viscoelastic properties of soft materials at the microscale is proposed. This approach is based on the adoption of a microsystem whose mechanical structure can be reduced to a compliant four bar linkage where the connecting rod is substituted by the tissue sample. A procedure to identify both stiffness and damping coefficients of the tissue is then applied to the developed hardware. Particularly, stiffness is calculated solving the static equations of the mechanism in a desired configuration, while the damping coefficient is inferred from the dynamic equations, which are written under the hypothesis that the sample tissue is excited by a variable compression force characterized by a suitable wave form. The whole procedure is implemented by making use of a control system.

Original languageEnglish
Article number15
JournalMicromachines
Volume9
Issue number1
DOIs
Publication statusPublished - Dec 30 2017

Fingerprint

MEMS
Tissue
Damping
Stiffness
Connecting rods
Microsystems
Compaction
Hardware
Control systems

Keywords

  • Control
  • MEMS
  • Soft tissue
  • Tweezers
  • Viscous coefficient

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Di Giamberardino, P., Bagolini, A., Bellutti, P., Rudas, I., Verotti, M., Botta, F., & Belfiore, N. P. (2017). New MEMS tweezers for the viscoelastic characterization of soft materials at the microscale. Micromachines, 9(1), [15]. https://doi.org/10.3390/mi9010015

New MEMS tweezers for the viscoelastic characterization of soft materials at the microscale. / Di Giamberardino, Paolo; Bagolini, Alvise; Bellutti, Pierluigi; Rudas, I.; Verotti, Matteo; Botta, Fabio; Belfiore, Nicola P.

In: Micromachines, Vol. 9, No. 1, 15, 30.12.2017.

Research output: Contribution to journalArticle

Di Giamberardino, P, Bagolini, A, Bellutti, P, Rudas, I, Verotti, M, Botta, F & Belfiore, NP 2017, 'New MEMS tweezers for the viscoelastic characterization of soft materials at the microscale', Micromachines, vol. 9, no. 1, 15. https://doi.org/10.3390/mi9010015
Di Giamberardino, Paolo ; Bagolini, Alvise ; Bellutti, Pierluigi ; Rudas, I. ; Verotti, Matteo ; Botta, Fabio ; Belfiore, Nicola P. / New MEMS tweezers for the viscoelastic characterization of soft materials at the microscale. In: Micromachines. 2017 ; Vol. 9, No. 1.
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