New far-red and near-infrared fluorescent probes with large stokes shifts for dual covalent labeling of DNA

Thomas Ehrenschwender, Balázs R. Varga, P. Kele, Hans Achim Wagenknecht

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Shifty chemistry! Fluorescent coumarin dyes with large Stokes shifts are incorporated postsynthetically into oligonucleotides and cmbined to FRET pairs that shift the emission into the far-red/near-infrared regime. Certain FRET pairs show good potential for use in strand displacement assays.

Original languageEnglish
Pages (from-to)1761-1764
Number of pages4
JournalChemistry - An Asian Journal
Volume5
Issue number8
DOIs
Publication statusPublished - Aug 2 2010

Fingerprint

Fluorescent Dyes
Oligonucleotides
Labeling
Assays
Coloring Agents
Infrared radiation
DNA
coumarin

Keywords

  • Cycloaddition
  • Energy transfer
  • Fluorescence
  • Megastokes
  • Oligonucleotide

ASJC Scopus subject areas

  • Chemistry(all)
  • Medicine(all)

Cite this

New far-red and near-infrared fluorescent probes with large stokes shifts for dual covalent labeling of DNA. / Ehrenschwender, Thomas; Varga, Balázs R.; Kele, P.; Wagenknecht, Hans Achim.

In: Chemistry - An Asian Journal, Vol. 5, No. 8, 02.08.2010, p. 1761-1764.

Research output: Contribution to journalArticle

Ehrenschwender, Thomas ; Varga, Balázs R. ; Kele, P. ; Wagenknecht, Hans Achim. / New far-red and near-infrared fluorescent probes with large stokes shifts for dual covalent labeling of DNA. In: Chemistry - An Asian Journal. 2010 ; Vol. 5, No. 8. pp. 1761-1764.
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