Újabb adatok izovanillin típusú molekulák édes ízének molekuláris hátteré ro{combining double acute accent}l

Translated title of the contribution: New facts about the molecular background of isovanilline-type stweeteners

Ńoemi Kálḿan, Erzśebet Magyarné-Jeszenszki, Tibor Kurtán, Sándor Antus

Research output: Contribution to journalArticle

Abstract

As a continuation of our studies on the relationship between structure and sweet taste of isovanilline-type sweeteners, (3-hydroxy-4-methoxy)benzyl- benzoate (17) and -salicylate (17c), analogues of dihidrochalcone-type sweetener analogues of (+)-phyllodulcin [(+)-5] and CH-401 (14c) have been synthesized. Surprisingly, 17c has been found to be tastless, while 17e was slightly sweet. These observations could be explained by the current hypothesis on the receptor model for isovanilline-type sweet derivatives.

Translated title of the contributionNew facts about the molecular background of isovanilline-type stweeteners
Original languageHungarian
Pages (from-to)15-19
Number of pages5
JournalActa pharmaceutica Hungarica
Volume84
Issue number1
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Pharmaceutical Science

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