New data of nonlinear phenomenon in the heterogeneous enantioselective hydrogenation of activated ketones

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Results on nonlinear phenomenon (NLP) in the liquid phase hydrogenation of methyl benzoylformate (MBF) and pyruvaldehyde dimethyl acetal (PA) on chiral Pt-cinchona catalyst are reported for the first time (enantiomeric excess 90-95%). The new data support the conclusions of the NLP studies on ethyl pyruvate (EP) and ketopantolactone (KPL). Namely, the order of the adsorption strengths of the parent cinchona alkaloids are: CD > CN > QN ~ QD and the results of the NLP measurements indirectly verify the so-called 1:1 model of enantioselection. The new data, however, call attention to a new, substrate and modifier dependent phenomenon, which necessitates further experiments for a better understanding of the mechanism of the Orito reaction.

Original languageEnglish
Pages (from-to)46-51
Number of pages6
JournalCatalysis Letters
Volume124
Issue number1-2
DOIs
Publication statusPublished - Aug 2008

Keywords

  • Asymmetric hydrogenation
  • Cinchona alkaloids
  • Ketones
  • Nonlinear phenomenon
  • Platinum

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Fingerprint Dive into the research topics of 'New data of nonlinear phenomenon in the heterogeneous enantioselective hydrogenation of activated ketones'. Together they form a unique fingerprint.

  • Cite this