Áj klinikai adatok a cukorbetegek metforminterápiá jával kapcsolatban

Translated title of the contribution: New clinical data with metformin therapy in patients with diabetes mellitus

Research output: Contribution to journalReview article

7 Citations (Scopus)


Metformin is widely used for treating patients with type 2 diabetes mellitus. Recently, new options of metformin therapy were highlighted by several clinical observations. Accordingly, the benefit of metformin for treating patients with type 1 diabetes was documented (as an add-on therapy to insulin, primarily in adult patients with the phenotype of type 2 diabetes). In addition, epidemiological studies unequivocally documented that metformin is associated with lower cancer morbidity and mortality rates in type 2 diabetic patients. Metformin was used in diabetic patients with systolic heart failure and the results proved to be promising in a clinical trial. The use of metformin in type 2 diabetic patients with insulin treatment can result in a decrease in insulin dose, an improvement in glycaemic control, a beneficial effect in weight changes and a decrease in risk of macrovascular complications. A late and prolonged beneficial effect of a former favourable metabolic milieu could be expected even in the subsequent years after terminating a randomized controlled trial with metformin. Although the new clinical observations should be considered encouraging, our clinical practice should strictly follow the current guidelines based on the label of metformin.

Original languageHungarian
Pages (from-to)2025-2030
Number of pages6
JournalOrvosi hetilap
Issue number49
Publication statusPublished - Dec 1 2010


ASJC Scopus subject areas

  • Medicine(all)

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