Cloned DNA probes can now be targeted directly into selected genes, to identify those at risk of inherited diseases. This review focuses on the use of such probes in the diagnosis of familial hypercholesterolaemia, by detecting mutations in the gene for the low-density lipoprotein receptor.
|Number of pages||4|
|Journal||Clinical Chemistry and Enzymology Communications|
|Publication status||Published - Jan 1 1988|
ASJC Scopus subject areas
- Clinical Biochemistry