New advances in the rehabilitation of CNS diseases applying rTMS

J. Málly, Trevor W. Stone

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Transcranial magnetic stimulation (TMS) can directly stimulate the CNS, modifying the brain's plasticity to enhance the behavior of the paretic extremities. Studies with low-frequency repetitive TMS (rTMS) on the intact hemisphere and those with high frequencies on the affected hemisphere could increase the speed of movement in the hand affected by CNS injury. Stimulation of the motor pathway may contribute to faster improvement in patients with spinal cord injury. Symptoms of Parkinson's disease (such as cognition and working memory, neglect syndrome and global aphasia) can be influenced by rTMS. However, the site of stimulation and the parameters of rTMS are different. Processes that contribute to the behavior of rTMS include the modification of brain plasticity, induction of neurogenesis, growth of new fibers in the spinal cord or all of these together. According to previous research, rTMS may be suitable as an add-on therapy to rehabilitation in CNS diseases.

Original languageEnglish
Pages (from-to)165-177
Number of pages13
JournalExpert Review of Neurotherapeutics
Volume7
Issue number2
DOIs
Publication statusPublished - Feb 2007

Fingerprint

Transcranial Magnetic Stimulation
Central Nervous System Diseases
Rehabilitation
Efferent Pathways
Aphasia
Neurogenesis
Brain
Spinal Cord Injuries
Short-Term Memory
Cognition
Parkinson Disease
Spinal Cord
Extremities
Hand
Wounds and Injuries
Growth
Research
Therapeutics

Keywords

  • Parkinson's disease
  • Post-stroke state
  • Spinal cord injury
  • TMS
  • Transcranial magnetic stimulation
  • Working memory

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

New advances in the rehabilitation of CNS diseases applying rTMS. / Málly, J.; Stone, Trevor W.

In: Expert Review of Neurotherapeutics, Vol. 7, No. 2, 02.2007, p. 165-177.

Research output: Contribution to journalArticle

@article{50244dceeb2a4af9aed8a6df7faf36ec,
title = "New advances in the rehabilitation of CNS diseases applying rTMS",
abstract = "Transcranial magnetic stimulation (TMS) can directly stimulate the CNS, modifying the brain's plasticity to enhance the behavior of the paretic extremities. Studies with low-frequency repetitive TMS (rTMS) on the intact hemisphere and those with high frequencies on the affected hemisphere could increase the speed of movement in the hand affected by CNS injury. Stimulation of the motor pathway may contribute to faster improvement in patients with spinal cord injury. Symptoms of Parkinson's disease (such as cognition and working memory, neglect syndrome and global aphasia) can be influenced by rTMS. However, the site of stimulation and the parameters of rTMS are different. Processes that contribute to the behavior of rTMS include the modification of brain plasticity, induction of neurogenesis, growth of new fibers in the spinal cord or all of these together. According to previous research, rTMS may be suitable as an add-on therapy to rehabilitation in CNS diseases.",
keywords = "Parkinson's disease, Post-stroke state, Spinal cord injury, TMS, Transcranial magnetic stimulation, Working memory",
author = "J. M{\'a}lly and Stone, {Trevor W.}",
year = "2007",
month = "2",
doi = "10.1586/14737175.7.2.165",
language = "English",
volume = "7",
pages = "165--177",
journal = "Expert Review of Neurotherapeutics",
issn = "1473-7175",
publisher = "Expert Reviews Ltd.",
number = "2",

}

TY - JOUR

T1 - New advances in the rehabilitation of CNS diseases applying rTMS

AU - Málly, J.

AU - Stone, Trevor W.

PY - 2007/2

Y1 - 2007/2

N2 - Transcranial magnetic stimulation (TMS) can directly stimulate the CNS, modifying the brain's plasticity to enhance the behavior of the paretic extremities. Studies with low-frequency repetitive TMS (rTMS) on the intact hemisphere and those with high frequencies on the affected hemisphere could increase the speed of movement in the hand affected by CNS injury. Stimulation of the motor pathway may contribute to faster improvement in patients with spinal cord injury. Symptoms of Parkinson's disease (such as cognition and working memory, neglect syndrome and global aphasia) can be influenced by rTMS. However, the site of stimulation and the parameters of rTMS are different. Processes that contribute to the behavior of rTMS include the modification of brain plasticity, induction of neurogenesis, growth of new fibers in the spinal cord or all of these together. According to previous research, rTMS may be suitable as an add-on therapy to rehabilitation in CNS diseases.

AB - Transcranial magnetic stimulation (TMS) can directly stimulate the CNS, modifying the brain's plasticity to enhance the behavior of the paretic extremities. Studies with low-frequency repetitive TMS (rTMS) on the intact hemisphere and those with high frequencies on the affected hemisphere could increase the speed of movement in the hand affected by CNS injury. Stimulation of the motor pathway may contribute to faster improvement in patients with spinal cord injury. Symptoms of Parkinson's disease (such as cognition and working memory, neglect syndrome and global aphasia) can be influenced by rTMS. However, the site of stimulation and the parameters of rTMS are different. Processes that contribute to the behavior of rTMS include the modification of brain plasticity, induction of neurogenesis, growth of new fibers in the spinal cord or all of these together. According to previous research, rTMS may be suitable as an add-on therapy to rehabilitation in CNS diseases.

KW - Parkinson's disease

KW - Post-stroke state

KW - Spinal cord injury

KW - TMS

KW - Transcranial magnetic stimulation

KW - Working memory

UR - http://www.scopus.com/inward/record.url?scp=33847285012&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33847285012&partnerID=8YFLogxK

U2 - 10.1586/14737175.7.2.165

DO - 10.1586/14737175.7.2.165

M3 - Article

C2 - 17286550

AN - SCOPUS:33847285012

VL - 7

SP - 165

EP - 177

JO - Expert Review of Neurotherapeutics

JF - Expert Review of Neurotherapeutics

SN - 1473-7175

IS - 2

ER -