Neuroplasticity and diaschisis phenomenon in central nervous system disorders

V. B. Voytenkov, J. Málly, N. V. Skripchenko, A. V. Kartashev

Research output: Contribution to journalReview article


The article presents phenomenon of diaschisis that was first described by Russian-Swiss neurologist Konstantin von Monakov at the beginning of the XX century. Diaschisis is a distant change of excitability and functioning of the neural tissues that occurs after the lesion of the brain. The diaschisis existence was later proved by pathological, neurophysiological methods such as somatosensory evoked potentials, transcranial magnetic stimulation, electroencephalography, magnetoencephalography and by neuroimaging (PET and MRI). Normalization of contralateral neurophysiological disorders does not always correlate with neurological symptoms; this fact causes some doubts about clinical significance of the phenomenon. Despite these doubts, clinical symptoms and signs, not connected with the lesion of the brain but caused by diaschisis were reported in some works. Besides the classic structural form, several additional types of diaschisis were proposed, such as functional, dynamic, connectional and connectomial. Among these types functional diaschisis is the best described one. In evaluation of the clinical significance of this phenomenon neuroplasticity have to be taken into account. Neuroplasticity may attenuate diaschisis; but neuroplasticity itself is modified by this phenomenon. Localization of the lesion plays crucial role here. Thus, modern neurorehabilitation techniques that are aimed on neuroplasticity induction, have to consider diaschisis phenomenon.

Original languageEnglish
Pages (from-to)188-193
Number of pages6
JournalNevrologicheskii Zhurnal
Issue number4
Publication statusPublished - Jan 1 2016



  • Diaschisis
  • Interhemispheric connections
  • Neuroplasticity
  • Neurorehabilitation

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health

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