Neuropeptides in the human superior cervical ganglion

Judit Baffi, T. Görcs, Felicia Slowik, M. Horváth, N. Lekka, E. Pásztor, M. Palkóvits

Research output: Contribution to journalArticle

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Abstract

Superior cervical ganglia from 7 human cadavers (3-7 h post mortem) were immunostained for tyrosine hydroxylase (TH), dopamine-β-hydroxylase (DBH) and 14 different neuropeptides. The results show that ganglionic cells contain TH, DBH, neuropeptide Y (NPY), somatostatin, vasoactive intestinal polypeptide (VIP) and calcitonin gene-related peptide (CGRP). These substances were present predominantly within large ganglionic cells. Inside the ganglion, the number and topographical distribution of various types of immunoreactive cells differed from one another. NPY and CGRP immunoreactivities were found in some TH-positive cells, but that co-localization never exceeded the 30% of the TH cells. Leu-enkephalin showed a weak immunoreactivity, which was restricted to fibers or varicosities. Neuropeptides like substance P, dynorphin A and B, cholecystokinin, galanin, corticotropin-releasing factor, thyreotropin-releasing hormone, angiotensin II and neurotensin showed no immunoreactivity in the human superior cervical ganglion.

Original languageEnglish
Pages (from-to)272-278
Number of pages7
JournalBrain Research
Volume570
Issue number1-2
DOIs
Publication statusPublished - Jan 20 1992

Fingerprint

Superior Cervical Ganglion
Neuropeptides
Tyrosine 3-Monooxygenase
Calcitonin Gene-Related Peptide
Neuropeptide Y
Leucine Enkephalin
Galanin
Dynorphins
Neurotensin
Corticotropin-Releasing Hormone
Vasoactive Intestinal Peptide
Cholecystokinin
Thyrotropin
Substance P
Mixed Function Oxygenases
Somatostatin
Cadaver
Ganglia
Angiotensin II
Dopamine

Keywords

  • Calcitonin gene-related peptide
  • Catecholamine
  • Human cervical ganglion
  • Immunohistochemistry
  • Leu-enkephalin
  • Neuropeptide Y
  • Somatostatin
  • Vasoactive intestinal polypeptide

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Neuropeptides in the human superior cervical ganglion. / Baffi, Judit; Görcs, T.; Slowik, Felicia; Horváth, M.; Lekka, N.; Pásztor, E.; Palkóvits, M.

In: Brain Research, Vol. 570, No. 1-2, 20.01.1992, p. 272-278.

Research output: Contribution to journalArticle

Baffi, J, Görcs, T, Slowik, F, Horváth, M, Lekka, N, Pásztor, E & Palkóvits, M 1992, 'Neuropeptides in the human superior cervical ganglion', Brain Research, vol. 570, no. 1-2, pp. 272-278. https://doi.org/10.1016/0006-8993(92)90591-V
Baffi J, Görcs T, Slowik F, Horváth M, Lekka N, Pásztor E et al. Neuropeptides in the human superior cervical ganglion. Brain Research. 1992 Jan 20;570(1-2):272-278. https://doi.org/10.1016/0006-8993(92)90591-V
Baffi, Judit ; Görcs, T. ; Slowik, Felicia ; Horváth, M. ; Lekka, N. ; Pásztor, E. ; Palkóvits, M. / Neuropeptides in the human superior cervical ganglion. In: Brain Research. 1992 ; Vol. 570, No. 1-2. pp. 272-278.
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