Neurolymphomatosis as a late relapse of non-Hodgkin's lymphoma detected by 18F-FDG PET/CT

A case report

K. Kajáry, Z. Molnár, I. Mikó, P. Barsi, Z. Lengyel, S. Szakáll

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Neurolymphomatosis is a rare condition defined as an infiltration of nerves, nerve roots or nervous plexuses by haematological malignancy. Its diagnosis may sometimes be difficult with conventional imaging techniques. This paper aims to emphasize the importance of this entity and the role of 18F-FDG PET/CT in this indication. We present the case of a 53-year-old male who complained of sharp pain in his right hip and right leg paresthesia after 2 years of complete remission from Non-Hodgkin's lymphoma. Physical examination and CT scan were negative and the lumbar MRI showed protrusion of L5-S1 disc. Physiotherapy, nonsteroid antiinflammatory drugs and steroids were inefficient. PET/CT was performed four months after the onset of the symptoms, revealing focal FDG uptake in the right S1 nerve root and linear FDG uptake along the right sacral plexus suggesting relapse. This was confirmed by histology.

Original languageEnglish
Pages (from-to)39-42
Number of pages4
JournalRevista Espanola de Medicina Nuclear e Imagen Molecular
Volume33
Issue number1
DOIs
Publication statusPublished - Jan 2014

Fingerprint

Lumbosacral Plexus
Marek Disease
Paresthesia
Fluorodeoxyglucose F18
Hematologic Neoplasms
Non-Hodgkin's Lymphoma
Physical Examination
Hip
Leg
Histology
Anti-Inflammatory Agents
Steroids
Recurrence
Pain
Pharmaceutical Preparations

Keywords

  • Diffuse large B-cell lymphoma
  • FDG
  • Neurolymphomatosis
  • Non-Hodgkin's lymphoma
  • PET/CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

@article{43e31ab5de244c9b86fad92ce8a9bb5b,
title = "Neurolymphomatosis as a late relapse of non-Hodgkin's lymphoma detected by 18F-FDG PET/CT: A case report",
abstract = "Neurolymphomatosis is a rare condition defined as an infiltration of nerves, nerve roots or nervous plexuses by haematological malignancy. Its diagnosis may sometimes be difficult with conventional imaging techniques. This paper aims to emphasize the importance of this entity and the role of 18F-FDG PET/CT in this indication. We present the case of a 53-year-old male who complained of sharp pain in his right hip and right leg paresthesia after 2 years of complete remission from Non-Hodgkin's lymphoma. Physical examination and CT scan were negative and the lumbar MRI showed protrusion of L5-S1 disc. Physiotherapy, nonsteroid antiinflammatory drugs and steroids were inefficient. PET/CT was performed four months after the onset of the symptoms, revealing focal FDG uptake in the right S1 nerve root and linear FDG uptake along the right sacral plexus suggesting relapse. This was confirmed by histology.",
keywords = "Diffuse large B-cell lymphoma, FDG, Neurolymphomatosis, Non-Hodgkin's lymphoma, PET/CT",
author = "K. Kaj{\'a}ry and Z. Moln{\'a}r and I. Mik{\'o} and P. Barsi and Z. Lengyel and S. Szak{\'a}ll",
year = "2014",
month = "1",
doi = "10.1016/j.remn.2013.03.004",
language = "English",
volume = "33",
pages = "39--42",
journal = "Revista Espanola de Medicina Nuclear e Imagen Molecular",
issn = "2253-654X",
publisher = "Elsevier Espana",
number = "1",

}

TY - JOUR

T1 - Neurolymphomatosis as a late relapse of non-Hodgkin's lymphoma detected by 18F-FDG PET/CT

T2 - A case report

AU - Kajáry, K.

AU - Molnár, Z.

AU - Mikó, I.

AU - Barsi, P.

AU - Lengyel, Z.

AU - Szakáll, S.

PY - 2014/1

Y1 - 2014/1

N2 - Neurolymphomatosis is a rare condition defined as an infiltration of nerves, nerve roots or nervous plexuses by haematological malignancy. Its diagnosis may sometimes be difficult with conventional imaging techniques. This paper aims to emphasize the importance of this entity and the role of 18F-FDG PET/CT in this indication. We present the case of a 53-year-old male who complained of sharp pain in his right hip and right leg paresthesia after 2 years of complete remission from Non-Hodgkin's lymphoma. Physical examination and CT scan were negative and the lumbar MRI showed protrusion of L5-S1 disc. Physiotherapy, nonsteroid antiinflammatory drugs and steroids were inefficient. PET/CT was performed four months after the onset of the symptoms, revealing focal FDG uptake in the right S1 nerve root and linear FDG uptake along the right sacral plexus suggesting relapse. This was confirmed by histology.

AB - Neurolymphomatosis is a rare condition defined as an infiltration of nerves, nerve roots or nervous plexuses by haematological malignancy. Its diagnosis may sometimes be difficult with conventional imaging techniques. This paper aims to emphasize the importance of this entity and the role of 18F-FDG PET/CT in this indication. We present the case of a 53-year-old male who complained of sharp pain in his right hip and right leg paresthesia after 2 years of complete remission from Non-Hodgkin's lymphoma. Physical examination and CT scan were negative and the lumbar MRI showed protrusion of L5-S1 disc. Physiotherapy, nonsteroid antiinflammatory drugs and steroids were inefficient. PET/CT was performed four months after the onset of the symptoms, revealing focal FDG uptake in the right S1 nerve root and linear FDG uptake along the right sacral plexus suggesting relapse. This was confirmed by histology.

KW - Diffuse large B-cell lymphoma

KW - FDG

KW - Neurolymphomatosis

KW - Non-Hodgkin's lymphoma

KW - PET/CT

UR - http://www.scopus.com/inward/record.url?scp=84893000139&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84893000139&partnerID=8YFLogxK

U2 - 10.1016/j.remn.2013.03.004

DO - 10.1016/j.remn.2013.03.004

M3 - Article

VL - 33

SP - 39

EP - 42

JO - Revista Espanola de Medicina Nuclear e Imagen Molecular

JF - Revista Espanola de Medicina Nuclear e Imagen Molecular

SN - 2253-654X

IS - 1

ER -