Neuroimmune correlates of sleep in depression: Role of cytokines

Research output: Chapter in Book/Report/Conference proceedingChapter


Sleep is an integrate part of mammalian life, although the sleeping patterns of different species significantly differ in amounts and pattern. However, it is not an independent variable because, during sleep, almost every physiologic parameter changes relative to wakefulness (Lavie 2001). Insomnia is rather frequent; its prevalence is between 10 and 50% of the general population, depending on the methods used to assess sleep problems and on the population studied (Ohayon and Caulet 1996). In addition, many psychiatric disorders (e.g., depression) as well as various medical conditions including infectious, malignant and inflammatory diseases, are associated with disordered sleep (Benca and Quintas 1997; Bloom, Owens, McGuinn, Nobile, Schaeffer, and Alario 2002).

Original languageEnglish
Title of host publicationNeuroimmunology of Sleep
Number of pages25
ISBN (Print)0387691448, 9780387691442
Publication statusPublished - Dec 1 2007


ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Neuroscience(all)

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