Neurochemistry of GABAergic System in Cerebral Cortex Chronically Exposed to Bromide In Vivo

Vladimir J. Balcar, Sandor L. Erdö, Ferenc Joó, Péter Kása, Joachim R. Wolff

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Abstract: Neurochemical correlates of GABAergic synaptic transmission [binding, uptake, metabolism, and tissue content of γ‐aminobutyric acid (GABA)] were investigated in the cortex of rats that had been given 27 mM bromide in drinking water for periods of time ranging from 1 day to 1 month. No effect of bromide on any of the parameters was found and it is concluded that chronic administration of bromide has no profound effect on GABAergic inhibitory system in the rat cortex.

Original languageEnglish
Pages (from-to)167-169
Number of pages3
JournalJournal of neurochemistry
Issue number1
Publication statusPublished - Jan 1987



  • Bromide
  • GABAergic synaptic transmission
  • Rat cerebral cortex

ASJC Scopus subject areas

  • Biochemistry
  • Cellular and Molecular Neuroscience

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