Neural circuitry that governs Drosophila male courtship behavior

Petra Stockinger, Duda Kvitsiani, Shay Rotkopf, L. Tirián, Barry J. Dickson

Research output: Contribution to journalArticle

343 Citations (Scopus)

Abstract

Male-specific fruitless (fru) products (FruM) are both necessary and sufficient to "hardwire" the potential for male courtship behavior into the Drosophila nervous system. FruM is expressed in ∼2% of neurons in the male nervous system, but not in the female. We have targeted the insertion of GAL4 into the fru locus, allowing us to visualize and manipulate the FruM-expressing neurons in the male as well as their counterparts in the female. We present evidence that these neurons are directly and specifically involved in male courtship behavior and that at least some of them are interconnected in a circuit. This circuit includes olfactory neurons required for the behavioral response to sex pheromones. Anatomical differences in this circuit that might account for the dramatic differences in male and female sexual behavior are not apparent.

Original languageEnglish
Pages (from-to)795-807
Number of pages13
JournalCell
Volume121
Issue number5
DOIs
Publication statusPublished - Jun 3 2005

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Courtship
Drosophila
Neurons
Neurology
Networks (circuits)
Sex Attractants
Nervous System
Sexual Behavior

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Stockinger, P., Kvitsiani, D., Rotkopf, S., Tirián, L., & Dickson, B. J. (2005). Neural circuitry that governs Drosophila male courtship behavior. Cell, 121(5), 795-807. https://doi.org/10.1016/j.cell.2005.04.026

Neural circuitry that governs Drosophila male courtship behavior. / Stockinger, Petra; Kvitsiani, Duda; Rotkopf, Shay; Tirián, L.; Dickson, Barry J.

In: Cell, Vol. 121, No. 5, 03.06.2005, p. 795-807.

Research output: Contribution to journalArticle

Stockinger, P, Kvitsiani, D, Rotkopf, S, Tirián, L & Dickson, BJ 2005, 'Neural circuitry that governs Drosophila male courtship behavior', Cell, vol. 121, no. 5, pp. 795-807. https://doi.org/10.1016/j.cell.2005.04.026
Stockinger P, Kvitsiani D, Rotkopf S, Tirián L, Dickson BJ. Neural circuitry that governs Drosophila male courtship behavior. Cell. 2005 Jun 3;121(5):795-807. https://doi.org/10.1016/j.cell.2005.04.026
Stockinger, Petra ; Kvitsiani, Duda ; Rotkopf, Shay ; Tirián, L. ; Dickson, Barry J. / Neural circuitry that governs Drosophila male courtship behavior. In: Cell. 2005 ; Vol. 121, No. 5. pp. 795-807.
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