Nepresol in the treatment of hypertension of major severity

M. Nemeth, I. Tenyi, A. Pár

Research output: Contribution to journalArticle

Abstract

Fifty patients with arterial hypertension of various causes were treated with a combination consisting of Nepresol, a beta-adrenergic receptor-blocking agent and a diuretic. Duration of treatment ranged between 3 months and 5 years. A significant reduction of blood pressure was attained in all of the cases, with a return of the values to the normal range in a high proportion of the patients. The renal function did not deteriorate during therapy, but owing to potassium loss regular potassium replacement was required in the majority of the cases. Allergic reactions appeared in two cases. Neither SLE nor rheumatoid arthritis was encountered. Positive ANF reaction and a significant elevation of the Rose-Waaler titre were demonstrated in a number of cases. The benefits as well as the hazards of the therapeutic use of hydrazine derivatives are pointed out.

Original languageEnglish
Pages (from-to)105-117
Number of pages13
JournalActa Medica Academiae Scientiarum Hungaricae
Volume36
Issue number1
Publication statusPublished - 1979

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Hydralazine
hydrazine
Potassium
Hypertension
Adrenergic beta-Antagonists
Receptors, Adrenergic, beta
Atrial Natriuretic Factor
Therapeutic Uses
Diuretics
Rheumatoid Arthritis
Hypersensitivity
Reference Values
Blood Pressure
Kidney
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nepresol in the treatment of hypertension of major severity. / Nemeth, M.; Tenyi, I.; Pár, A.

In: Acta Medica Academiae Scientiarum Hungaricae, Vol. 36, No. 1, 1979, p. 105-117.

Research output: Contribution to journalArticle

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