Nephropathia nem inzulindependens (2. típusú) diabetes mellitusban.

Translated title of the contribution: Nephropathy in non-insulin-dependent (type-2) diabetes mellitus

Research output: Contribution to journalArticle

Abstract

There is a dramatic increase in the incidence of end-stage renal disease in non-insulin dependent diabetes mellitus (NIDDM) requiring renal replacement therapy. The most important risk factors of the onset of nephropathy in NIDDM are genetic predisposition (history of diabetes, hypertension and cardiovascular events in first-degree relatives), hypertension, quality of glycaemic control and smoking. These risk factors play an important role also in the progression of diabetic nephropathy. In about 20-25% of NIDDM patients nondiabetic renal diseases cause the renal damage (other primary nephropathies, ischaemic nephropathy). NIDDM is mainly the part of metabolic x syndrome (hypertension, obesity, dyslipidaemia, impaired glucose tolerance or NIDDM) and, for this reason, all members of metabolic x syndrome has to be involved in treatment strategies e.g. blood pressure "subnormalization", aggressive glycaemic control, cessation of smoking, the treatment of obesity and dyslipidaemia with diet, physical activity and antilipidaemic drugs, as well as restriction of dietary protein and salt intake. The successful prevention and treatment of diabetic nephropathy needs the development of an interdisciplinary interaction that involves general practitioners, diabetologists and nephrologists.

Original languageHungarian
Pages (from-to)609-614
Number of pages6
JournalOrvosi Hetilap
Volume141
Issue number12
Publication statusPublished - Mar 19 2000

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Type 2 Diabetes Mellitus
Diabetic Nephropathies
Dyslipidemias
Hypertension
Obesity
Kidney
Withholding Treatment
Glucose Intolerance
Renal Replacement Therapy
Dietary Proteins
Genetic Predisposition to Disease
Quality Control
General Practitioners
Chronic Kidney Failure
Salts
Smoking
Exercise
Diet
Blood Pressure
Incidence

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nephropathia nem inzulindependens (2. típusú) diabetes mellitusban. / Nagy, J.; Wittmann, I.

In: Orvosi Hetilap, Vol. 141, No. 12, 19.03.2000, p. 609-614.

Research output: Contribution to journalArticle

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