Nefrogén szisztémás fibrosis

Translated title of the contribution: Nephrogenic systemic fibrosis

István Pinter, Katalin Vágási, I. Wittmann, J. Nagy

Research output: Contribution to journalArticle

Abstract

The nephrogenic systemic fibrosis - referred to in the literature earlier as nephrogenic fibrotizing dermopathy - is a rare clinical entity that develops in patients with renal disease. Its development has been described mainly after the usage of a gadolinium-based MRI contrast medium in patients with impaired renal function, mainly in dialysed patients. The nephrogenic systemic fibrosis is characterized by fibrosis evolving in the distal part of the extremities, and in more severe cases involving the lung, the liver, heart and sceletal muscles. The disease may have a fast progression and fatal outcome if it involves multiple organ systems, in approximately 5% of the cases. Until now, no evidence-based therapy of nephrogenic systemic fibrosis is known, however, in single cases an amelioration has been described after renal transplantation and plasmapheresis, and remission has been described after extracorporal photopheresis.

Original languageHungarian
Pages (from-to)1801-1804
Number of pages4
JournalOrvosi Hetilap
Volume148
Issue number38
DOIs
Publication statusPublished - Sep 23 2007

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Nephrogenic Fibrosing Dermopathy
Photopheresis
Kidney
Fatal Outcome
Plasmapheresis
Gadolinium
Kidney Transplantation
Contrast Media
Myocardium
Fibrosis
Extremities
Lung
Liver
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nefrogén szisztémás fibrosis. / Pinter, István; Vágási, Katalin; Wittmann, I.; Nagy, J.

In: Orvosi Hetilap, Vol. 148, No. 38, 23.09.2007, p. 1801-1804.

Research output: Contribution to journalArticle

Pinter, István ; Vágási, Katalin ; Wittmann, I. ; Nagy, J. / Nefrogén szisztémás fibrosis. In: Orvosi Hetilap. 2007 ; Vol. 148, No. 38. pp. 1801-1804.
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