Neonatal monocular enucleation-induced cross-modal effects observed in the cortex of adult rat

J. Toldi, I. Rojik, O. Fehér

Research output: Contribution to journalArticle

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Abstract

The cortices of neonatally enucleated rats were explored for somatosensory responses with special reference to an extension into the occipital cortex. Monocular enucleation was performed on rats at birth. The animals were raised and from the age of three months the activity evoked by either electric stimulation of the vibrissa pad or bending of the vibrissae was tested in the contralateral cortex by electric recording and autoradiography. It was found that early enucleation caused an expansion of the somatosensory responses, among others into the visual area. Neurons responsive to visual and somatosen- sory stimuli were demonstrated in the anterior part of the primary and secondary visual areas, contralateral to the enucleation. Electrophysiological and autoradiographic studies unambiguously proved that early enucleation exerted a significant cross-modal effect on the somatosensory responsive area. Abbreviations: LGB, lateral geniculate body; PSTH, post-stimulus time histograms.

Original languageEnglish
Pages (from-to)105-114
Number of pages10
JournalNeuroscience
Volume62
Issue number1
DOIs
Publication statusPublished - 1994

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Vibrissae
Geniculate Bodies
Occipital Lobe
Autoradiography
Electric Stimulation
Parturition
Neurons

ASJC Scopus subject areas

  • Neuroscience(all)

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Neonatal monocular enucleation-induced cross-modal effects observed in the cortex of adult rat. / Toldi, J.; Rojik, I.; Fehér, O.

In: Neuroscience, Vol. 62, No. 1, 1994, p. 105-114.

Research output: Contribution to journalArticle

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