Negative impact of the noseclip on high-frequency respiratory impedance measurements

Cindy Thamrin, Gergely Albu, Peter D. Sly, Z. Hantos

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The noseclip is conventionally used in lung function testing to prevent leakage via the nasal compartments. However, some subjects exhibit a velum-opening reflex which may affect results. We performed forced oscillation measurements at frequencies (8-256 Hz) that include the first antiresonance, comparing the noseclip with a cotton wool nose plug to eliminate upper airway contribution. Three sets of measurements were made in 18 adults: with and without noseclip, and with cotton wool. Velum opening during noseclip measurements was monitored using a nasal pressure transducer. A significantly greater proportion of subjects produced a characteristic distortion to the first antiresonance with the noseclip than with either no noseclip or with cotton wool. Distortion of the spectrum coincided with the transmission of oscillations into the nasal cavity. Thus, the noseclip cannot be used in high-frequency forced oscillation measurements because of the velum reflex. The cotton wool plug offers a simple alternative. This effect has unknown impact in other lung function tests.

Original languageEnglish
Pages (from-to)115-118
Number of pages4
JournalRespiratory Physiology and Neurobiology
Volume165
Issue number1
DOIs
Publication statusPublished - Jan 1 2009

Fingerprint

Wool
Electric Impedance
Nose
Reflex
Pressure Transducers
Nasal Cavity
Respiratory Function Tests
Lung

Keywords

  • Antiresonance
  • Forced oscillation technique
  • Lung function tests
  • Noseclip

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine
  • Neuroscience(all)

Cite this

Negative impact of the noseclip on high-frequency respiratory impedance measurements. / Thamrin, Cindy; Albu, Gergely; Sly, Peter D.; Hantos, Z.

In: Respiratory Physiology and Neurobiology, Vol. 165, No. 1, 01.01.2009, p. 115-118.

Research output: Contribution to journalArticle

Thamrin, Cindy ; Albu, Gergely ; Sly, Peter D. ; Hantos, Z. / Negative impact of the noseclip on high-frequency respiratory impedance measurements. In: Respiratory Physiology and Neurobiology. 2009 ; Vol. 165, No. 1. pp. 115-118.
@article{ae877114385245229508a15506a8f6e7,
title = "Negative impact of the noseclip on high-frequency respiratory impedance measurements",
abstract = "The noseclip is conventionally used in lung function testing to prevent leakage via the nasal compartments. However, some subjects exhibit a velum-opening reflex which may affect results. We performed forced oscillation measurements at frequencies (8-256 Hz) that include the first antiresonance, comparing the noseclip with a cotton wool nose plug to eliminate upper airway contribution. Three sets of measurements were made in 18 adults: with and without noseclip, and with cotton wool. Velum opening during noseclip measurements was monitored using a nasal pressure transducer. A significantly greater proportion of subjects produced a characteristic distortion to the first antiresonance with the noseclip than with either no noseclip or with cotton wool. Distortion of the spectrum coincided with the transmission of oscillations into the nasal cavity. Thus, the noseclip cannot be used in high-frequency forced oscillation measurements because of the velum reflex. The cotton wool plug offers a simple alternative. This effect has unknown impact in other lung function tests.",
keywords = "Antiresonance, Forced oscillation technique, Lung function tests, Noseclip",
author = "Cindy Thamrin and Gergely Albu and Sly, {Peter D.} and Z. Hantos",
year = "2009",
month = "1",
day = "1",
doi = "10.1016/j.resp.2008.10.014",
language = "English",
volume = "165",
pages = "115--118",
journal = "Respiratory Physiology and Neurobiology",
issn = "1569-9048",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - Negative impact of the noseclip on high-frequency respiratory impedance measurements

AU - Thamrin, Cindy

AU - Albu, Gergely

AU - Sly, Peter D.

AU - Hantos, Z.

PY - 2009/1/1

Y1 - 2009/1/1

N2 - The noseclip is conventionally used in lung function testing to prevent leakage via the nasal compartments. However, some subjects exhibit a velum-opening reflex which may affect results. We performed forced oscillation measurements at frequencies (8-256 Hz) that include the first antiresonance, comparing the noseclip with a cotton wool nose plug to eliminate upper airway contribution. Three sets of measurements were made in 18 adults: with and without noseclip, and with cotton wool. Velum opening during noseclip measurements was monitored using a nasal pressure transducer. A significantly greater proportion of subjects produced a characteristic distortion to the first antiresonance with the noseclip than with either no noseclip or with cotton wool. Distortion of the spectrum coincided with the transmission of oscillations into the nasal cavity. Thus, the noseclip cannot be used in high-frequency forced oscillation measurements because of the velum reflex. The cotton wool plug offers a simple alternative. This effect has unknown impact in other lung function tests.

AB - The noseclip is conventionally used in lung function testing to prevent leakage via the nasal compartments. However, some subjects exhibit a velum-opening reflex which may affect results. We performed forced oscillation measurements at frequencies (8-256 Hz) that include the first antiresonance, comparing the noseclip with a cotton wool nose plug to eliminate upper airway contribution. Three sets of measurements were made in 18 adults: with and without noseclip, and with cotton wool. Velum opening during noseclip measurements was monitored using a nasal pressure transducer. A significantly greater proportion of subjects produced a characteristic distortion to the first antiresonance with the noseclip than with either no noseclip or with cotton wool. Distortion of the spectrum coincided with the transmission of oscillations into the nasal cavity. Thus, the noseclip cannot be used in high-frequency forced oscillation measurements because of the velum reflex. The cotton wool plug offers a simple alternative. This effect has unknown impact in other lung function tests.

KW - Antiresonance

KW - Forced oscillation technique

KW - Lung function tests

KW - Noseclip

UR - http://www.scopus.com/inward/record.url?scp=57749110415&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=57749110415&partnerID=8YFLogxK

U2 - 10.1016/j.resp.2008.10.014

DO - 10.1016/j.resp.2008.10.014

M3 - Article

VL - 165

SP - 115

EP - 118

JO - Respiratory Physiology and Neurobiology

JF - Respiratory Physiology and Neurobiology

SN - 1569-9048

IS - 1

ER -