Chiptechnikák alkalmazásának szüksé gessége gyomortumorokban

Translated title of the contribution: Necessity of application of the chip technology in gastric cancer

Research output: Contribution to journalArticle

Abstract

Gastric cancer is one of the most frequent cancer type in the world today. This fact emphasises the importance of identification of useful diagnostic and prognostic markers for gastric cancers in their earliest stages. Aim of this review is to summarize the genetic knowledge related to gastric carcinogenesis and progression and to offer a survey of the gene expression pattern changes and their functional classification. Microarray results show that the gene expression pattern detected in gastric cancers highly depends on the histological type and heterogenity of the sample, array type and data analyzing softwares. Recent experiments point out the changes of not just the alterations of tumor suppression, apoptosis, cell cycle regulation and signal transduction, but tumor cell metabolism and cell-microenvironment interactions, too. All results show connection to and complete the already known molecular background of gastric cancer.

Original languageHungarian
Pages (from-to)939-947
Number of pages9
JournalOrvosi Hetilap
Volume145
Issue number18
Publication statusPublished - May 2004

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Stomach Neoplasms
Technology
Cellular Microenvironment
Gene Expression
Neoplasms
Cell Communication
Signal Transduction
Stomach
Cell Cycle
Carcinogenesis
Software
Apoptosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chiptechnikák alkalmazásának szüksé gessége gyomortumorokban. / Galamb, O.; Sípos, F.; Molnár, B.; Tulassay, Z.

In: Orvosi Hetilap, Vol. 145, No. 18, 05.2004, p. 939-947.

Research output: Contribution to journalArticle

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