In this work, an environmental friendly process of nano hydroxyapatite (nHap) preparation was demonstrated by using eggshell. The synthesised materials were dependent on the mixing ratio (wt.%) of the calcined eggshell and phosphoric acid. Electrospun nanocomposites were successfully manufactured and applied in bone tissue engineering. Celulose acetate - nHap scaffolds were proved to promote favorable adhesion and growth of osteoblasts. Morover, nHap was introduced as new bone graft material. μCT analysis and histomorphometric analysis showed that nHap from eggshell showed much more bone formation compared to unfilled control group in only 8 weeks. nHap was easily degraded in vivo, further study for scaffold would be required. Considering that the eggshell is easily available and cheap, nHA from the eggshell can be good calcium source in tissue engineering.
ASJC Scopus subject areas
- Biomedical Engineering