NALOXONE ANTAGONISES EFFECT OF α-GLIADIN ON LEUCOCYTE MIGRATION IN PATIENTS WITH COELIAC DISEASE

Károly Horváth, Erzsebét Walcz, László Gráf, Hedvig Bodánszky, Dezsö Schuler

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The effect of naloxone on inhibition of leucocyte migration by α-gliadin was examined in 24 patients with coeliac disease. In all cases in which α-gliadin inhibited leucocyte migration, naloxone blocked this inhibitory effect, which suggests that the effect of gliadin on lymphocytes from patients with coeliac disease may be mediated through opioid-like receptors.

Original languageEnglish
Pages (from-to)184-185
Number of pages2
JournalThe Lancet
Volume326
Issue number8448
DOIs
Publication statusPublished - Jul 27 1985

ASJC Scopus subject areas

  • Medicine(all)

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