N-Substituted trimethylsilylcarbamates as silylating and/or methoxime derivatizing reagents for gas chromatographic analysis

D. Knausz, A. Meszticzky, J. Rohonczy, Zs Kolos, B. Csákvári, F. Szederkényi, K. Újszászy

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

N-Substituted trimethylsilylcarbamates were tested as derivatizing reagents for gas chromatographic analysis. N,N-Dimethyltrimethylsilylcarbamate was found to be a suitable agent for direct trimethylsilylation of the salts of alkaloids without previous liberation of the bases. N-Methoxy-N,O-bistrimethylsilylcarbamate was found to react simultaneously and quantitatively with the hydroxy and keto groups of steroids, resulting in the corresponding methoxime trimethylsilyl derivatives.

Original languageEnglish
Pages (from-to)183-190
Number of pages8
JournalJournal of Chromatography A
Volume365
Issue numberC
DOIs
Publication statusPublished - Sep 19 1986

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Alkaloids
Gas chromatography
Gas Chromatography
Salts
Steroids
Derivatives
N,N'-monomethylenebis(pyridiniumaldoxime)

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

N-Substituted trimethylsilylcarbamates as silylating and/or methoxime derivatizing reagents for gas chromatographic analysis. / Knausz, D.; Meszticzky, A.; Rohonczy, J.; Kolos, Zs; Csákvári, B.; Szederkényi, F.; Újszászy, K.

In: Journal of Chromatography A, Vol. 365, No. C, 19.09.1986, p. 183-190.

Research output: Contribution to journalArticle

Knausz, D. ; Meszticzky, A. ; Rohonczy, J. ; Kolos, Zs ; Csákvári, B. ; Szederkényi, F. ; Újszászy, K. / N-Substituted trimethylsilylcarbamates as silylating and/or methoxime derivatizing reagents for gas chromatographic analysis. In: Journal of Chromatography A. 1986 ; Vol. 365, No. C. pp. 183-190.
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