N-Substituted trimethylsilylcarbamates as silylating and/or methoxime derivatizing reagents for gas chromatographic analysis

D. Knausz, A. Meszticzky, J. Rohonczy, Zs Kolos, B. Csákvári, F. Szederkényi, K. Ujszászy

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Abstract

N-Substituted trimethylsilylcarbamates were tested as derivatizing reagents for gas chromatographic analysis. N,N-Dimethyltrimethylsilylcarbamate was found to be a suitable agent for direct trimethylsilylation of the salts of alkaloids without previous liberation of the bases. N-Methoxy-N,O-bistrimethylsilylcarbamate was found to react simultaneously and quantitatively with the hydroxy and keto groups of steroids, resulting in the corresponding methoxime trimethylsilyl derivatives.

Original languageEnglish
Pages (from-to)183-190
Number of pages8
JournalJournal of Chromatography A
Volume365
Issue numberC
DOIs
Publication statusPublished - Sep 19 1986

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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