Myofibroblastisches Sarkom des Zungengrundes. Fallbericht und Literaturübersicht

Translated title of the contribution: Myofibroblastic sarcoma of the base of tongue: CCase report and review of the literature

Zoltán Takácsi-Nagy, Györgyi Muraközy, Péter Pogány, János Fodor, Zsolt Orosz

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background: Mesenchymal malignancies with myofibroblastic differentiation exhibit a spectrum from low-grade myofibroblastic sarcoma mimicking fibromatosis to pleomorphic high-grade sarcoma. Low-grade myofibroblastic sarcoma shows a wide anatomic distribution with a predilection for the head-and-neck region; however, intermediate- and high-grade myofibroblastic sarcomas in this localization are exceptional. Case Report: A 56-year-old woman with intermediate-grade myofibroblastic sarcoma of the base of tongue is presented. She was treated with surgical excision, but computed tomography proved local residual tumor. Reexcision and chemotherapy were refused by the patient. Irradiation was given to a total dose of 66 Gy. Result: 50 months after completion of radiotherapy, the patient is in good health without any evidence of disease. According to the review of the literature, base of tongue as the primary site of myofibroblastic sarcoma has not been published so far. Conclusion: Similarly to the low-grade form, intermediate- and high-grade myofibroblastic sarcomas may also occur in the head-and-neck region. In case of incomplete excision, radiotherapy may be an effective treatment.

Translated title of the contributionMyofibroblastic sarcoma of the base of tongue: CCase report and review of the literature
Original languageGerman
Pages (from-to)198-201
Number of pages4
JournalStrahlentherapie und Onkologie
Volume185
Issue number3
DOIs
Publication statusPublished - Mar 1 2009

Keywords

  • Base of tongue
  • Myofibroblastic sarcoma
  • Radiotherapy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Oncology

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