Myofibre abnormalities of orbicular muscle in malposition of the eyelid

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Fifty-five cases of senile entropion and ectropion have been studied electron microscopically. In both senile entropion and ectropion, significant ultrastructural abnormalities were found in the orbicular muscle fibers, such as a disruption of fibers, Z line streaming, rod formation, Z line duplication and cytoplasmic body formation. These alterations have been described only in neuromuscular disorders and systemic diseases affecting the skeletal muscles. The authors' observations have confirmed that these abnormalities are not specific signs of any given disease; rather they represent the ultrastructural background of impaired muscle function independently of the etiology of the disease.

Original languageEnglish
Pages (from-to)205-218
Number of pages14
JournalActa Morphologica Academiae Scientiarum Hungaricae
Issue number4
Publication statusPublished - 1977


ASJC Scopus subject areas

  • Anatomy

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