Myelinated perikarya and dendrites in lateral geniculate nucleus of adult cat following chronic cortical deafferentation

J. Hámori, V. L. Silakov

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Chronic (one year) cortical deafferentation resulted in the appearance of myelinated neuronal perikarya and dendritic processes in the lateral geniculate nucleus (LGN) of the cat. Four per cent of all nerve cell bodies, both large and small, were observed to be covered partially or totally by compact myelin sheath. The myelination of the dendrites was confined to the most proximal portion of the processes. A comparison of the fine structural features of the myelinated cell bodies and dendrites with those from intact LGN indicate that both surviving projection neurons and local interneurons may become myelinated. It is suggested that the unorthodox myelination of nerve cell somata and dendrites is caused primarily by the massive deafferentation of the nucleus. This indicates a relationship between synaptic input and the process of myelination of the postsynaptic nerve cells.

Original languageEnglish
Pages (from-to)879-888
Number of pages10
JournalJournal of Neurocytology
Volume10
Issue number5
DOIs
Publication statusPublished - Oct 1981

Fingerprint

Geniculate Bodies
Dendrites
Cats
Neurons
Carisoprodol
Interneurons
Myelin Sheath
Cell Body

ASJC Scopus subject areas

  • Neuroscience(all)
  • Histology
  • Anatomy
  • Cell Biology

Cite this

Myelinated perikarya and dendrites in lateral geniculate nucleus of adult cat following chronic cortical deafferentation. / Hámori, J.; Silakov, V. L.

In: Journal of Neurocytology, Vol. 10, No. 5, 10.1981, p. 879-888.

Research output: Contribution to journalArticle

@article{96b62b71a4fb4a51bf8ec7fc3dea15c9,
title = "Myelinated perikarya and dendrites in lateral geniculate nucleus of adult cat following chronic cortical deafferentation",
abstract = "Chronic (one year) cortical deafferentation resulted in the appearance of myelinated neuronal perikarya and dendritic processes in the lateral geniculate nucleus (LGN) of the cat. Four per cent of all nerve cell bodies, both large and small, were observed to be covered partially or totally by compact myelin sheath. The myelination of the dendrites was confined to the most proximal portion of the processes. A comparison of the fine structural features of the myelinated cell bodies and dendrites with those from intact LGN indicate that both surviving projection neurons and local interneurons may become myelinated. It is suggested that the unorthodox myelination of nerve cell somata and dendrites is caused primarily by the massive deafferentation of the nucleus. This indicates a relationship between synaptic input and the process of myelination of the postsynaptic nerve cells.",
author = "J. H{\'a}mori and Silakov, {V. L.}",
year = "1981",
month = "10",
doi = "10.1007/BF01262659",
language = "English",
volume = "10",
pages = "879--888",
journal = "Journal of Neurocytology",
issn = "0300-4864",
publisher = "Kluwer Academic Publishers",
number = "5",

}

TY - JOUR

T1 - Myelinated perikarya and dendrites in lateral geniculate nucleus of adult cat following chronic cortical deafferentation

AU - Hámori, J.

AU - Silakov, V. L.

PY - 1981/10

Y1 - 1981/10

N2 - Chronic (one year) cortical deafferentation resulted in the appearance of myelinated neuronal perikarya and dendritic processes in the lateral geniculate nucleus (LGN) of the cat. Four per cent of all nerve cell bodies, both large and small, were observed to be covered partially or totally by compact myelin sheath. The myelination of the dendrites was confined to the most proximal portion of the processes. A comparison of the fine structural features of the myelinated cell bodies and dendrites with those from intact LGN indicate that both surviving projection neurons and local interneurons may become myelinated. It is suggested that the unorthodox myelination of nerve cell somata and dendrites is caused primarily by the massive deafferentation of the nucleus. This indicates a relationship between synaptic input and the process of myelination of the postsynaptic nerve cells.

AB - Chronic (one year) cortical deafferentation resulted in the appearance of myelinated neuronal perikarya and dendritic processes in the lateral geniculate nucleus (LGN) of the cat. Four per cent of all nerve cell bodies, both large and small, were observed to be covered partially or totally by compact myelin sheath. The myelination of the dendrites was confined to the most proximal portion of the processes. A comparison of the fine structural features of the myelinated cell bodies and dendrites with those from intact LGN indicate that both surviving projection neurons and local interneurons may become myelinated. It is suggested that the unorthodox myelination of nerve cell somata and dendrites is caused primarily by the massive deafferentation of the nucleus. This indicates a relationship between synaptic input and the process of myelination of the postsynaptic nerve cells.

UR - http://www.scopus.com/inward/record.url?scp=0019834719&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019834719&partnerID=8YFLogxK

U2 - 10.1007/BF01262659

DO - 10.1007/BF01262659

M3 - Article

C2 - 7310480

AN - SCOPUS:0019834719

VL - 10

SP - 879

EP - 888

JO - Journal of Neurocytology

JF - Journal of Neurocytology

SN - 0300-4864

IS - 5

ER -